Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACHWYH_RS06420 Genome accession   NZ_CP172084
Coordinates   1284249..1285592 (-) Length   447 a.a.
NCBI ID   WP_032823983.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA81666     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1279249..1290592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYH_RS06390 - 1280167..1280439 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  ACHWYH_RS06395 - 1280580..1281170 (-) 591 WP_005691398.1 YjaG family protein -
  ACHWYH_RS06400 nudC 1281206..1282000 (-) 795 WP_112103055.1 NAD(+) diphosphatase -
  ACHWYH_RS06405 nfuA 1282067..1282663 (-) 597 WP_005652130.1 Fe-S biogenesis protein NfuA -
  ACHWYH_RS06410 - 1282739..1283425 (-) 687 WP_112103056.1 ComF family protein -
  ACHWYH_RS06415 tnpA 1283797..1284252 (-) 456 WP_005652127.1 IS200/IS605 family transposase -
  ACHWYH_RS06420 comE 1284249..1285592 (-) 1344 WP_032823983.1 type IV pilus secretin PilQ Machinery gene
  ACHWYH_RS06425 comD 1285602..1286015 (-) 414 WP_070828390.1 pilus assembly protein PilP Machinery gene
  ACHWYH_RS06430 comC 1286012..1286533 (-) 522 WP_112103057.1 competence protein ComC Machinery gene
  ACHWYH_RS06435 comB 1286530..1287036 (-) 507 WP_005656467.1 competence protein ComB Machinery gene
  ACHWYH_RS06440 comA 1287037..1287834 (-) 798 WP_112103058.1 pilus assembly protein PilM Machinery gene
  ACHWYH_RS06445 - 1287933..1290527 (+) 2595 WP_112103059.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49328.60 Da        Isoelectric Point: 7.1111

>NTDB_id=1065055 ACHWYH_RS06420 WP_032823983.1 1284249..1285592(-) (comE) [Haemophilus influenzae strain GA81666]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLDVLKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=1065055 ACHWYH_RS06420 WP_032823983.1 1284249..1285592(-) (comE) [Haemophilus influenzae strain GA81666]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACATTAGAGCAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAAGG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTAGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACGACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGCGCTTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACGTCGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCGCATAT
TTTAAAAGCGGGGGAAACGTTAGATGTTTTGAAACAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

96.18

99.553

0.957
  comE Haemophilus influenzae Rd KW20

95.955

99.553

0.955
  comE Glaesserella parasuis strain SC1401

52.471

95.078

0.499
  pilQ Vibrio campbellii strain DS40M4

42.959

93.736

0.403
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.17

0.389
  pilQ Vibrio cholerae strain A1552

42.233

92.17

0.389

Multiple sequence alignment