Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   ACHWYH_RS06435 Genome accession   NZ_CP172084
Coordinates   1286530..1287036 (-) Length   168 a.a.
NCBI ID   WP_005656467.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA81666     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1281530..1292036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYH_RS06405 nfuA 1282067..1282663 (-) 597 WP_005652130.1 Fe-S biogenesis protein NfuA -
  ACHWYH_RS06410 - 1282739..1283425 (-) 687 WP_112103056.1 ComF family protein -
  ACHWYH_RS06415 tnpA 1283797..1284252 (-) 456 WP_005652127.1 IS200/IS605 family transposase -
  ACHWYH_RS06420 comE 1284249..1285592 (-) 1344 WP_032823983.1 type IV pilus secretin PilQ Machinery gene
  ACHWYH_RS06425 comD 1285602..1286015 (-) 414 WP_070828390.1 pilus assembly protein PilP Machinery gene
  ACHWYH_RS06430 comC 1286012..1286533 (-) 522 WP_112103057.1 competence protein ComC Machinery gene
  ACHWYH_RS06435 comB 1286530..1287036 (-) 507 WP_005656467.1 competence protein ComB Machinery gene
  ACHWYH_RS06440 comA 1287037..1287834 (-) 798 WP_112103058.1 pilus assembly protein PilM Machinery gene
  ACHWYH_RS06445 - 1287933..1290527 (+) 2595 WP_112103059.1 penicillin-binding protein 1A -
  ACHWYH_RS06450 - 1290600..1291445 (+) 846 WP_112103060.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ACHWYH_RS06455 - 1291598..1291927 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19752.67 Da        Isoelectric Point: 9.4939

>NTDB_id=1065058 ACHWYH_RS06435 WP_005656467.1 1286530..1287036(-) (comB) [Haemophilus influenzae strain GA81666]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMRIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=1065058 ACHWYH_RS06435 WP_005656467.1 1286530..1287036(-) (comB) [Haemophilus influenzae strain GA81666]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGCCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCGAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

98.81

100

0.988
  comB Haemophilus influenzae Rd KW20

98.81

100

0.988

Multiple sequence alignment