Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACHWYH_RS05735 Genome accession   NZ_CP172084
Coordinates   1156991..1158211 (-) Length   406 a.a.
NCBI ID   WP_112103478.1    Uniprot ID   -
Organism   Haemophilus influenzae strain GA81666     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1151991..1163211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYH_RS05700 - 1153154..1153360 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACHWYH_RS05705 - 1153446..1153652 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACHWYH_RS05710 - 1153738..1153944 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  ACHWYH_RS05715 cueR 1154021..1154407 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  ACHWYH_RS05720 metJ 1154421..1154738 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  ACHWYH_RS05725 rho 1154986..1156248 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  ACHWYH_RS05730 pilD 1156302..1156994 (-) 693 WP_112103479.1 A24 family peptidase Machinery gene
  ACHWYH_RS05735 pilC 1156991..1158211 (-) 1221 WP_112103478.1 type II secretion system F family protein Machinery gene
  ACHWYH_RS05740 pilB 1158208..1159602 (-) 1395 WP_112103477.1 GspE/PulE family protein Machinery gene
  ACHWYH_RS05745 pilA 1159599..1160048 (-) 450 WP_110426612.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  ACHWYH_RS05750 ampD 1160163..1160723 (+) 561 WP_112103476.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACHWYH_RS05755 corC 1161346..1162245 (+) 900 WP_110426610.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46131.35 Da        Isoelectric Point: 9.7214

>NTDB_id=1065048 ACHWYH_RS05735 WP_112103478.1 1156991..1158211(-) (pilC) [Haemophilus influenzae strain GA81666]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISCGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTHIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1065048 ACHWYH_RS05735 WP_112103478.1 1156991..1158211(-) (pilC) [Haemophilus influenzae strain GA81666]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCACATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATCCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAAACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCAGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment