Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACG3JH_RS02260 Genome accession   NZ_CP171731
Coordinates   463655..464329 (+) Length   224 a.a.
NCBI ID   WP_003104260.1    Uniprot ID   A0A0E2UA77
Organism   Streptococcus parauberis strain DB-M1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 458655..469329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JH_RS02245 (ACG3JH_02245) pstB 459460..460218 (+) 759 WP_003104047.1 phosphate ABC transporter ATP-binding protein PstB -
  ACG3JH_RS02250 (ACG3JH_02250) phoU 460284..460937 (+) 654 WP_003103398.1 phosphate signaling complex protein PhoU -
  ACG3JH_RS02255 (ACG3JH_02255) - 461001..463538 (+) 2538 WP_003105115.1 M1 family metallopeptidase -
  ACG3JH_RS02260 (ACG3JH_02260) ciaR 463655..464329 (+) 675 WP_003104260.1 response regulator transcription factor Regulator
  ACG3JH_RS02265 (ACG3JH_02265) ciaH 464322..465626 (+) 1305 WP_045406827.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACG3JH_RS02270 (ACG3JH_02270) rpsT 465716..465949 (-) 234 WP_003105398.1 30S ribosomal protein S20 -
  ACG3JH_RS02275 (ACG3JH_02275) coaA 466018..466938 (-) 921 WP_003106953.1 type I pantothenate kinase -
  ACG3JH_RS02280 (ACG3JH_02280) - 467189..467788 (+) 600 WP_003103028.1 class I SAM-dependent methyltransferase -
  ACG3JH_RS02285 (ACG3JH_02285) - 467775..469052 (+) 1278 WP_003102832.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25767.68 Da        Isoelectric Point: 4.3994

>NTDB_id=1063708 ACG3JH_RS02260 WP_003104260.1 463655..464329(+) (ciaR) [Streptococcus parauberis strain DB-M1]
MIKILLVEDDLSLSNSIFDFLDDFADVLQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKDIHTAVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKLMDSSLYYKNLKVDTERNVVTVDEKEVELLGKEFELLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTKFVADLQTLRSVGYILKTNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1063708 ACG3JH_RS02260 WP_003104260.1 463655..464329(+) (ciaR) [Streptococcus parauberis strain DB-M1]
ATGATAAAAATATTATTAGTCGAAGATGATTTGAGTTTGTCCAATTCAATATTTGATTTTTTAGATGACTTTGCTGATGT
CTTACAAGTTTTTGATGGTGATGAGGGGCTTTATGAGGCTGAAAGTGGTGTCTATGACTTAATTTTGCTTGATTTAATGC
TTCCAGAAAAAGATGGTTTTCAAGTTTTAAAAGAGCTTAGGGAAAAAGATATTCATACAGCTGTGTTAATTATGACCGCT
AAAGAGAGTCTTGATGATAAAGGTCATGGTTTTGAATTAGGAGCTGATGATTATTTAACTAAGCCGTTTTATCTTGAAGA
ATTGAAGATGCGCATTCAAGCATTACTCAAACGTTCTGGAAAACTGATGGACAGTAGTCTATATTATAAAAATCTAAAAG
TTGATACAGAACGTAATGTCGTTACTGTTGATGAGAAGGAAGTGGAATTACTTGGAAAAGAGTTTGAATTACTTGTTTAT
TTCCTTCAAAATCAAAACGTTATTTTGCCAAAATCACAGATATTTGATCGAATTTGGGGATTTGATAGTGATACAACAAT
TTCAGTCGTAGAAGTTTATGTTTCAAAAATACGAAAAAAATTGAAGGGAACAAAATTTGTTGCTGATTTACAAACTCTTC
GGAGCGTTGGCTACATTTTAAAAACAAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UA77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae Rx1

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae D39

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae R6

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae TIGR4

83.71

98.661

0.826
  vicR Streptococcus mutans UA159

35.745

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.47

100

0.371
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.444

100

0.366

Multiple sequence alignment