Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACFKHK_RS05060 Genome accession   NZ_CP170760
Coordinates   950628..951299 (+) Length   223 a.a.
NCBI ID   WP_024392086.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 945628..956299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS05030 - 946335..947471 (+) 1137 WP_392462614.1 glycosyltransferase family 4 protein -
  ACFKHK_RS05035 - 947901..948086 (+) 186 WP_172071176.1 hypothetical protein -
  ACFKHK_RS05040 tnpB 948067..948417 (+) 351 WP_024407179.1 IS66 family insertion sequence element accessory protein TnpB -
  ACFKHK_RS05045 - 948469..948675 (+) 207 WP_002939754.1 hypothetical protein -
  ACFKHK_RS05050 - 948629..949981 (+) 1353 Protein_958 IS66-like element short variant transposase -
  ACFKHK_RS05055 - 950154..950531 (+) 378 WP_392462615.1 hypothetical protein -
  ACFKHK_RS05060 ciaR 950628..951299 (+) 672 WP_024392086.1 response regulator transcription factor Regulator
  ACFKHK_RS05065 ciaH 951292..952665 (+) 1374 WP_392462616.1 sensor histidine kinase Regulator
  ACFKHK_RS05070 - 952753..953970 (+) 1218 WP_392462617.1 transglutaminase domain-containing protein -
  ACFKHK_RS05075 rpsT 954004..954252 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  ACFKHK_RS05080 coaA 954311..955231 (-) 921 WP_392462618.1 type I pantothenate kinase -
  ACFKHK_RS05085 - 955307..955897 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25198.82 Da        Isoelectric Point: 4.2459

>NTDB_id=1059263 ACFKHK_RS05060 WP_024392086.1 950628..951299(+) (ciaR) [Streptococcus parasuis strain FZ2]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1059263 ACFKHK_RS05060 WP_024392086.1 950628..951299(+) (ciaR) [Streptococcus parasuis strain FZ2]
ATGATTAAGATACTGTTGGTAGAAGACGATTTAAGCCTTTCTAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGATTTAATTCTTTTAGATTTAATGT
TACCTGAGAAAGATGGTTTTCAAGTATTAAAAGAATTGCGTGAAAAAGGGGTCTCAACTCCTGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACGTACGGAGATGTTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAGTTCGATTTGTTGGTATAT
TTCTTACAGAATCAGAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCGAAAGTAAGGAAAAAATTGAAAGGAACCGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.238

100

0.892
  ciaR Streptococcus pneumoniae Rx1

88.789

100

0.888
  ciaR Streptococcus pneumoniae D39

88.789

100

0.888
  ciaR Streptococcus pneumoniae R6

88.789

100

0.888
  ciaR Streptococcus pneumoniae TIGR4

88.789

100

0.888
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.611

100

0.381
  vicR Streptococcus mutans UA159

35.043

100

0.368

Multiple sequence alignment