Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACFKHK_RS05065 Genome accession   NZ_CP170760
Coordinates   951292..952665 (+) Length   457 a.a.
NCBI ID   WP_392462616.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 946292..957665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS05030 - 946335..947471 (+) 1137 WP_392462614.1 glycosyltransferase family 4 protein -
  ACFKHK_RS05035 - 947901..948086 (+) 186 WP_172071176.1 hypothetical protein -
  ACFKHK_RS05040 tnpB 948067..948417 (+) 351 WP_024407179.1 IS66 family insertion sequence element accessory protein TnpB -
  ACFKHK_RS05045 - 948469..948675 (+) 207 WP_002939754.1 hypothetical protein -
  ACFKHK_RS05050 - 948629..949981 (+) 1353 Protein_958 IS66-like element short variant transposase -
  ACFKHK_RS05055 - 950154..950531 (+) 378 WP_392462615.1 hypothetical protein -
  ACFKHK_RS05060 ciaR 950628..951299 (+) 672 WP_024392086.1 response regulator transcription factor Regulator
  ACFKHK_RS05065 ciaH 951292..952665 (+) 1374 WP_392462616.1 sensor histidine kinase Regulator
  ACFKHK_RS05070 - 952753..953970 (+) 1218 WP_392462617.1 transglutaminase domain-containing protein -
  ACFKHK_RS05075 rpsT 954004..954252 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  ACFKHK_RS05080 coaA 954311..955231 (-) 921 WP_392462618.1 type I pantothenate kinase -
  ACFKHK_RS05085 - 955307..955897 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -
  ACFKHK_RS05090 - 955894..957171 (+) 1278 WP_392462619.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51412.53 Da        Isoelectric Point: 5.0148

>NTDB_id=1059264 ACFKHK_RS05065 WP_392462616.1 951292..952665(+) (ciaH) [Streptococcus parasuis strain FZ2]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTPNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSDLSLDKKNLGEIKEATVDSTFGGSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEDDGAMQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=1059264 ACFKHK_RS05065 WP_392462616.1 951292..952665(+) (ciaH) [Streptococcus parasuis strain FZ2]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCCTTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTGCTGATGAAAGTGATTCTGCAGAATCTAATTCAGATACACCAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTATAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGCAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACTTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGATGATGGCGCTATGC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGCGATAAA
AAGAAAATTTTTGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTTGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAGGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCAAGATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae D39

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae R6

50.439

99.781

0.503
  ciaH Streptococcus pneumoniae TIGR4

50.439

99.781

0.503
  ciaH Streptococcus mutans UA159

49.669

99.125

0.492

Multiple sequence alignment