Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACFKHK_RS00350 Genome accession   NZ_CP170760
Coordinates   60828..62180 (+) Length   450 a.a.
NCBI ID   WP_392462185.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 55828..67180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS00340 - 56898..58166 (+) 1269 WP_392462181.1 MerR family transcriptional regulator -
  ACFKHK_RS00345 comA 58663..60816 (+) 2154 WP_392462183.1 peptide cleavage/export ABC transporter ComA Regulator
  ACFKHK_RS00350 comB 60828..62180 (+) 1353 WP_392462185.1 bacteriocin secretion accessory protein Regulator
  ACFKHK_RS00355 - 62569..62748 (+) 180 WP_024392853.1 hypothetical protein -
  ACFKHK_RS00360 - 62749..62949 (+) 201 WP_239604410.1 hypothetical protein -
  ACFKHK_RS00365 - 62966..63157 (+) 192 WP_024392851.1 hypothetical protein -
  ACFKHK_RS00370 - 63517..64386 (-) 870 WP_312220929.1 cysteine ABC transporter substrate-binding protein -
  ACFKHK_RS00375 - 64399..65145 (-) 747 WP_392462188.1 amino acid ABC transporter ATP-binding protein -
  ACFKHK_RS00380 - 65150..65827 (-) 678 WP_024392848.1 amino acid ABC transporter permease -
  ACFKHK_RS00385 - 65808..66467 (-) 660 WP_239604822.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50863.49 Da        Isoelectric Point: 4.8239

>NTDB_id=1059242 ACFKHK_RS00350 WP_392462185.1 60828..62180(+) (comB) [Streptococcus parasuis strain FZ2]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCYQLETLASTIDQQN
ATIASQNQAAKQSQLELDKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQVAQSEDAVASQESFIAQIDNQI
SQVETQLASYKLQYASAGVQQSYTNSLDSQSASLKAQYLTKVGQEMTLLSSQLRELEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTANQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1059242 ACFKHK_RS00350 WP_392462185.1 60828..62180(+) (comB) [Streptococcus parasuis strain FZ2]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACAGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTTAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTGGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCTATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCTGCAAAACAATCACAATTGGAATTGGATAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGGTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCATCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCAGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCAATCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

48.998

99.778

0.489
  comB Streptococcus pneumoniae D39

47.333

100

0.473
  comB Streptococcus pneumoniae R6

47.333

100

0.473
  comB Streptococcus pneumoniae Rx1

47.333

100

0.473
  comB Streptococcus pneumoniae TIGR4

46.889

100

0.469
  comB Streptococcus mitis NCTC 12261

46

100

0.46
  comB Streptococcus mitis SK321

45.778

100

0.458

Multiple sequence alignment