Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACFKHK_RS00345 Genome accession   NZ_CP170760
Coordinates   58663..60816 (+) Length   717 a.a.
NCBI ID   WP_392462183.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 53663..65816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS00330 - 54327..55073 (+) 747 WP_392462177.1 hypothetical protein -
  ACFKHK_RS00335 - 55078..56790 (+) 1713 WP_392462179.1 ABC transporter ATP-binding protein -
  ACFKHK_RS00340 - 56898..58166 (+) 1269 WP_392462181.1 MerR family transcriptional regulator -
  ACFKHK_RS00345 comA 58663..60816 (+) 2154 WP_392462183.1 peptide cleavage/export ABC transporter ComA Regulator
  ACFKHK_RS00350 comB 60828..62180 (+) 1353 WP_392462185.1 bacteriocin secretion accessory protein Regulator
  ACFKHK_RS00355 - 62569..62748 (+) 180 WP_024392853.1 hypothetical protein -
  ACFKHK_RS00360 - 62749..62949 (+) 201 WP_239604410.1 hypothetical protein -
  ACFKHK_RS00365 - 62966..63157 (+) 192 WP_024392851.1 hypothetical protein -
  ACFKHK_RS00370 - 63517..64386 (-) 870 WP_312220929.1 cysteine ABC transporter substrate-binding protein -
  ACFKHK_RS00375 - 64399..65145 (-) 747 WP_392462188.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81120.40 Da        Isoelectric Point: 7.0405

>NTDB_id=1059241 ACFKHK_RS00345 WP_392462183.1 58663..60816(+) (comA) [Streptococcus parasuis strain FZ2]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMAPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHIFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTI
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDQKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYDPYKGEIRLNNVNINQIDKQTLRQHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1059241 ACFKHK_RS00345 WP_392462183.1 58663..60816(+) (comA) [Streptococcus parasuis strain FZ2]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTAGATACACGAGACTGTGGTGTGGCAGCGCTTGCTATGATCTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCCCATGTGGTAAAAGATGGCACGTTACTACATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGGCTCCCAAACCGGAATATCAACCTCATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTCGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTTCCAAATCAGATGAAAACAACATTAGGTGTCATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATGCCCAAGAGTATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATATTTTTCATCTACCAATGTCATTTTTTGCTACTCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTATTGGCATTGCCAATCTATACTATA
ATCATTTTTGCGTTTATGAAACCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
TATTGAAGATATTAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCAATTCTTTGGTTAGGAGCCTGTCTTGTTATGGATCAGAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACGTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAACTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGACCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCAGCATATT
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATCTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
AATTGACTTCTGATGGAGCTGGAATCTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACTCTAATTTTTATTGCACATCGGTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGGTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.637

100

0.796
  comA Streptococcus pneumoniae D39

79.637

100

0.796
  comA Streptococcus pneumoniae R6

79.637

100

0.796
  comA Streptococcus mitis NCTC 12261

79.498

100

0.795
  comA Streptococcus pneumoniae TIGR4

79.358

100

0.794
  comA Streptococcus mitis SK321

79.358

100

0.794
  comA Streptococcus gordonii str. Challis substr. CH1

77.127

100

0.771
  comA/nlmT Streptococcus mutans UA159

63.877

100

0.639

Multiple sequence alignment