Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACFKHJ_RS04850 Genome accession   NZ_CP170759
Coordinates   936805..937476 (+) Length   223 a.a.
NCBI ID   WP_392453163.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 931805..942476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHJ_RS04840 - 933692..934630 (+) 939 WP_277745710.1 DPM/DPG synthase family glycosyltransferase -
  ACFKHJ_RS04845 - 934638..936626 (+) 1989 WP_392453162.1 hypothetical protein -
  ACFKHJ_RS04850 ciaR 936805..937476 (+) 672 WP_392453163.1 response regulator transcription factor Regulator
  ACFKHJ_RS04855 ciaH 937469..938842 (+) 1374 WP_392453165.1 sensor histidine kinase Regulator
  ACFKHJ_RS04860 - 938930..939790 (+) 861 WP_392453167.1 transglutaminase domain-containing protein -
  ACFKHJ_RS04865 - 939812..940147 (+) 336 WP_392453168.1 hypothetical protein -
  ACFKHJ_RS04870 rpsT 940182..940430 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  ACFKHJ_RS04875 coaA 940489..941409 (-) 921 WP_237396439.1 type I pantothenate kinase -
  ACFKHJ_RS04880 - 941485..942075 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25226.87 Da        Isoelectric Point: 4.2408

>NTDB_id=1059208 ACFKHJ_RS04850 WP_392453163.1 936805..937476(+) (ciaR) [Streptococcus parasuis strain FZ1]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPEKDGFQVLKELREKGISTPVLITTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDITVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1059208 ACFKHJ_RS04850 WP_392453163.1 936805..937476(+) (ciaR) [Streptococcus parasuis strain FZ1]
ATGATAAAAATATTATTGATCGAAGACGATTTAAGCCTTTCTAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGATTTAATTCTTTTAGATTTAATGT
TACCTGAGAAAGATGGTTTTCAAGTATTAAAAGAATTGCGTGAAAAAGGGATCTCAACTCCTGTTCTGATTACGACAGCC
AAGGAAGGCCTAGATGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACATACGGAGATATTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAGTTCGATTTGTTGGTATAT
TTCTTACAGAACCAGAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCAAAAGTAAGGAAAAAATTGAAAGGAACCGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.686

100

0.897
  ciaR Streptococcus pneumoniae Rx1

89.686

100

0.897
  ciaR Streptococcus pneumoniae D39

89.686

100

0.897
  ciaR Streptococcus pneumoniae R6

89.686

100

0.897
  ciaR Streptococcus pneumoniae TIGR4

89.686

100

0.897
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.053

100

0.386
  vicR Streptococcus mutans UA159

34.615

100

0.363

Multiple sequence alignment