Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACFKHJ_RS04855 Genome accession   NZ_CP170759
Coordinates   937469..938842 (+) Length   457 a.a.
NCBI ID   WP_392453165.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 932469..943842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHJ_RS04840 - 933692..934630 (+) 939 WP_277745710.1 DPM/DPG synthase family glycosyltransferase -
  ACFKHJ_RS04845 - 934638..936626 (+) 1989 WP_392453162.1 hypothetical protein -
  ACFKHJ_RS04850 ciaR 936805..937476 (+) 672 WP_392453163.1 response regulator transcription factor Regulator
  ACFKHJ_RS04855 ciaH 937469..938842 (+) 1374 WP_392453165.1 sensor histidine kinase Regulator
  ACFKHJ_RS04860 - 938930..939790 (+) 861 WP_392453167.1 transglutaminase domain-containing protein -
  ACFKHJ_RS04865 - 939812..940147 (+) 336 WP_392453168.1 hypothetical protein -
  ACFKHJ_RS04870 rpsT 940182..940430 (-) 249 WP_171988421.1 30S ribosomal protein S20 -
  ACFKHJ_RS04875 coaA 940489..941409 (-) 921 WP_237396439.1 type I pantothenate kinase -
  ACFKHJ_RS04880 - 941485..942075 (+) 591 WP_171988423.1 class I SAM-dependent methyltransferase -
  ACFKHJ_RS04885 - 942072..943349 (+) 1278 WP_392453169.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51372.41 Da        Isoelectric Point: 5.0148

>NTDB_id=1059209 ACFKHJ_RS04855 WP_392453165.1 937469..938842(+) (ciaH) [Streptococcus parasuis strain FZ1]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTTNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSDLSLDKKNLGEIKEATVDSTFGGSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEDDGAIQVTANIKDKSVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=1059209 ACFKHJ_RS04855 WP_392453165.1 937469..938842(+) (ciaH) [Streptococcus parasuis strain FZ1]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCATTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAC
GGAAATATTGCTGATGAAAGTGATTCTGCAGAATCTAATTCAGATACAACAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGCAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCTATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTTTGGAAAGTAGCGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGATGATGGCGCTATAC
AAGTGACAGCCAATATCAAAGATAAGTCAGTTTACTTTACGGTAGCGGACAATGGATTGGGTATCAGTGATAGTGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTAAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCGAGATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae D39

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae R6

50.658

99.781

0.505
  ciaH Streptococcus pneumoniae TIGR4

50.658

99.781

0.505
  ciaH Streptococcus mutans UA159

50.11

99.125

0.497

Multiple sequence alignment