Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACFKHJ_RS00355 Genome accession   NZ_CP170759
Coordinates   59602..60954 (+) Length   450 a.a.
NCBI ID   WP_392452714.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 54602..65954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHJ_RS00340 - 56465..56617 (+) 153 WP_079269043.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACFKHJ_RS00345 - 56804..56965 (+) 162 WP_172006749.1 hypothetical protein -
  ACFKHJ_RS00350 comA 57437..59590 (+) 2154 WP_237395556.1 peptide cleavage/export ABC transporter ComA Regulator
  ACFKHJ_RS00355 comB 59602..60954 (+) 1353 WP_392452714.1 bacteriocin secretion accessory protein Regulator
  ACFKHJ_RS00360 - 61342..61521 (+) 180 WP_024392853.1 hypothetical protein -
  ACFKHJ_RS00365 - 61522..61722 (+) 201 WP_239604410.1 hypothetical protein -
  ACFKHJ_RS00370 - 61739..61930 (+) 192 WP_024392851.1 hypothetical protein -
  ACFKHJ_RS00375 - 62289..63158 (-) 870 WP_392452716.1 cysteine ABC transporter substrate-binding protein -
  ACFKHJ_RS00380 - 63171..63917 (-) 747 WP_172036451.1 amino acid ABC transporter ATP-binding protein -
  ACFKHJ_RS00385 - 63922..64599 (-) 678 WP_171989020.1 amino acid ABC transporter permease -
  ACFKHJ_RS00390 - 64580..65239 (-) 660 WP_274505914.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50842.51 Da        Isoelectric Point: 4.7723

>NTDB_id=1059183 ACFKHJ_RS00355 WP_392452714.1 59602..60954(+) (comB) [Streptococcus parasuis strain FZ1]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVTKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCYQLETLASTIDQQN
ATIASQNQAAKQSQLELDKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQVAQSEDAVASQESFIAQIDNQI
SQVETQLASYKLQYASAGVQQSYTNSLDSQSASLKALYLNKVGQEMTLLSSQLRELEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIADVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1059183 ACFKHJ_RS00355 WP_392452714.1 59602..60954(+) (comB) [Streptococcus parasuis strain FZ1]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTACTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTGAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTAGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCTATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCCGCAAAACAATCACAATTGGAATTGGATAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGGTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCATCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCAGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCTATATTTAAACAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCAGATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

48.552

99.778

0.484
  comB Streptococcus pneumoniae D39

46.889

100

0.469
  comB Streptococcus pneumoniae R6

46.889

100

0.469
  comB Streptococcus pneumoniae Rx1

46.889

100

0.469
  comB Streptococcus pneumoniae TIGR4

46.444

100

0.464
  comB Streptococcus mitis NCTC 12261

45.556

100

0.456
  comB Streptococcus mitis SK321

45.333

100

0.453

Multiple sequence alignment