Detailed information NTG1052169

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACE2AN_RS02535
• Genome accession: NZ_CP169564
• Coordinates: 491655..493808 (-)
• Length: 717 a.a.
• NCBI ID: WP_375060587.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6_2F1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 486655..498808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE2AN_RS02505	-	486987..487316 (-)	330	WP_047499345.1	hypothetical protein	-
ACE2AN_RS02510	-	487592..487930 (+)	339	WP_000876675.1	LytTR family DNA-binding domain-containing protein	-
ACE2AN_RS02515	comE/blpR	487935..488672 (+)	738	WP_001219120.1	LytTR family DNA-binding domain-containing protein	Regulator
ACE2AN_RS02520	-	488686..490026 (+)	1341	WP_061365610.1	sensor histidine kinase	-
ACE2AN_RS02525	blpC	490071..490226 (-)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
ACE2AN_RS02530	-	490283..491644 (-)	1362	WP_375060586.1	bacteriocin secretion accessory protein	-
ACE2AN_RS02535	comA/nlmT	491655..493808 (-)	2154	WP_375060587.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACE2AN_RS02540	blpK	494090..494338 (+)	249	WP_000379965.1	bacteriocin-like peptide BlpK	-
ACE2AN_RS02545	cipB	494582..494731 (+)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator
ACE2AN_RS02550	-	494827..494946 (+)	120	WP_001833623.1	PncF family bacteriocin immunity protein	-
ACE2AN_RS02555	-	495672..496476 (+)	805	Protein_502	IS5 family transposase	-
ACE2AN_RS02560	blpM	496626..496880 (+)	255	WP_000379877.1	two-peptide bacteriocin subunit BlpM	-
ACE2AN_RS02565	blpN	496896..497099 (+)	204	WP_375060588.1	two-peptide bacteriocin subunit BlpN	-
ACE2AN_RS02570	-	497343..497576 (+)	234	WP_000379963.1	hypothetical protein	-
ACE2AN_RS02575	-	497608..498297 (+)	690	WP_000760523.1	CPBP family intramembrane glutamic endopeptidase	-
ACE2AN_RS02580	blpZ	498339..498572 (+)	234	WP_000276498.1	immunity protein BlpZ	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80748.72 Da
• Isoelectric Point: 7.4163

>NTDB_id=1052169 ACE2AN_RS02535 WP_375060587.1 491655..493808(-) (comA/nlmT) [Streptococcus pneumoniae strain 6_2F1]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKECFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VISSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1052169 ACE2AN_RS02535 WP_375060587.1 491655..493808(-) (comA/nlmT) [Streptococcus pneumoniae strain 6_2F1]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCTTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAATGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTCATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCAACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATCGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.888	99.721	0.717
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae D39	65.919	99.442	0.656
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus pneumoniae R6	65.919	99.442	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653
comA	Streptococcus pneumoniae TIGR4	65.638	99.442	0.653