Detailed information NTG1038138

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB345_RS04385
• Genome accession: NZ_CP167025
• Coordinates: 866951..867787 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 861951..872787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB345_RS04355 (ACB345_04355)	-	862436..862873 (+)	438	WP_031488279.1	hypothetical protein	-
ACB345_RS04360 (ACB345_04360)	-	862923..863834 (-)	912	WP_031488278.1	diacylglycerol kinase family protein	-
ACB345_RS04365 (ACB345_04365)	-	863951..864601 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB345_RS04370 (ACB345_04370)	-	864598..865038 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
ACB345_RS04375 (ACB345_04375)	ylqF	865257..866105 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
ACB345_RS04380 (ACB345_04380)	-	866095..866886 (+)	792	WP_031488275.1	ribonuclease HII	-
ACB345_RS04385 (ACB345_04385)	dprA	866951..867787 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
ACB345_RS04390 (ACB345_04390)	topA	867894..870023 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
ACB345_RS04395 (ACB345_04395)	-	870098..870955 (-)	858	Protein_817	LysR family transcriptional regulator	-
ACB345_RS04400 (ACB345_04400)	-	870995..871540 (+)	546	Protein_818	PTS sugar transporter subunit IIC	-
ACB345_RS04405 (ACB345_04405)	-	871555..872547 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=1038138 ACB345_RS04385 WP_031488274.1 866951..867787(+) (dprA) [Streptococcus pyogenes strain Isolate]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1038138 ACB345_RS04385 WP_031488274.1 866951..867787(+) (dprA) [Streptococcus pyogenes strain Isolate]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363