Detailed information NTG1037972

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB335_RS04870
• Genome accession: NZ_CP167022
• Coordinates: 937564..938400 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 4
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 932564..943400

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB335_RS04840 (ACB335_04840)	-	933049..933486 (+)	438	WP_031488279.1	hypothetical protein	-
ACB335_RS04845 (ACB335_04845)	-	933536..934447 (-)	912	WP_031488278.1	diacylglycerol kinase family protein	-
ACB335_RS04850 (ACB335_04850)	-	934564..935214 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB335_RS04855 (ACB335_04855)	-	935211..935651 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
ACB335_RS04860 (ACB335_04860)	ylqF	935870..936718 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
ACB335_RS04865 (ACB335_04865)	-	936708..937499 (+)	792	WP_031488275.1	ribonuclease HII	-
ACB335_RS04870 (ACB335_04870)	dprA	937564..938400 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
ACB335_RS04875 (ACB335_04875)	topA	938507..940636 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
ACB335_RS04880 (ACB335_04880)	-	940711..941568 (-)	858	Protein_914	LysR family transcriptional regulator	-
ACB335_RS04885 (ACB335_04885)	-	941608..942153 (+)	546	Protein_915	PTS sugar transporter subunit IIC	-
ACB335_RS04890 (ACB335_04890)	-	942168..943160 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=1037972 ACB335_RS04870 WP_031488274.1 937564..938400(+) (dprA) [Streptococcus pyogenes strain Isolate 4]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037972 ACB335_RS04870 WP_031488274.1 937564..938400(+) (dprA) [Streptococcus pyogenes strain Isolate 4]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363