Detailed information NTG1037642

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB332_RS04410
• Genome accession: NZ_CP167016
• Coordinates: 870045..870881 (+)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 10
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 865045..875881

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB332_RS04380 (ACB332_04380)	-	865593..865967 (+)	375	WP_011054498.1	hypothetical protein	-
ACB332_RS04385 (ACB332_04385)	-	866017..866928 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
ACB332_RS04390 (ACB332_04390)	-	867045..867695 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB332_RS04395 (ACB332_04395)	-	867692..868132 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
ACB332_RS04400 (ACB332_04400)	ylqF	868351..869199 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
ACB332_RS04405 (ACB332_04405)	-	869189..869980 (+)	792	WP_023080250.1	ribonuclease HII	-
ACB332_RS04410 (ACB332_04410)	dprA	870045..870881 (+)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
ACB332_RS04415 (ACB332_04415)	topA	870988..873117 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
ACB332_RS04420 (ACB332_04420)	-	873192..874076 (-)	885	Protein_822	LysR family transcriptional regulator	-
ACB332_RS04425 (ACB332_04425)	-	874089..874655 (+)	567	Protein_823	PTS sugar transporter subunit IIC	-
ACB332_RS04430 (ACB332_04430)	-	874670..875622 (+)	953	Protein_824	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=1037642 ACB332_RS04410 WP_020905195.1 870045..870881(+) (dprA) [Streptococcus pyogenes strain Isolate 10]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037642 ACB332_RS04410 WP_020905195.1 870045..870881(+) (dprA) [Streptococcus pyogenes strain Isolate 10]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367