Detailed information NTG1037424

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB355_RS04510
• Genome accession: NZ_CP167011
• Coordinates: 886377..887213 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 18
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 881377..892213

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB355_RS04480 (ACB355_04480)	-	881865..882299 (+)	435	WP_023079442.1	hypothetical protein	-
ACB355_RS04485 (ACB355_04485)	-	882349..883260 (-)	912	WP_023079407.1	diacylglycerol kinase family protein	-
ACB355_RS04490 (ACB355_04490)	-	883377..884027 (-)	651	WP_023079408.1	hemolysin III family protein	-
ACB355_RS04495 (ACB355_04495)	-	884024..884464 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB355_RS04500 (ACB355_04500)	ylqF	884683..885531 (+)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
ACB355_RS04505 (ACB355_04505)	-	885521..886312 (+)	792	WP_023079417.1	ribonuclease HII	-
ACB355_RS04510 (ACB355_04510)	dprA	886377..887213 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
ACB355_RS04515 (ACB355_04515)	topA	887320..889449 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
ACB355_RS04520 (ACB355_04520)	-	889524..890408 (-)	885	Protein_842	LysR family transcriptional regulator	-
ACB355_RS04525 (ACB355_04525)	-	890421..890974 (+)	554	Protein_843	PTS sugar transporter subunit IIC	-
ACB355_RS04530 (ACB355_04530)	-	890989..891981 (+)	993	WP_023078604.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1037424 ACB355_RS04510 WP_023079425.1 886377..887213(+) (dprA) [Streptococcus pyogenes strain Isolate 18]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037424 ACB355_RS04510 WP_023079425.1 886377..887213(+) (dprA) [Streptococcus pyogenes strain Isolate 18]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367