Detailed information NTG1037363

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB333_RS04475
• Genome accession: NZ_CP167010
• Coordinates: 892702..893538 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 20
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 887702..898538

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB333_RS04445 (ACB333_04450)	-	888256..888624 (+)	369	WP_010922310.1	hypothetical protein	-
ACB333_RS04450 (ACB333_04455)	-	888674..889585 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
ACB333_RS04455 (ACB333_04460)	-	889702..890352 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB333_RS04460 (ACB333_04465)	-	890349..890789 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB333_RS04465 (ACB333_04470)	ylqF	891008..891856 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
ACB333_RS04470 (ACB333_04475)	-	891846..892637 (+)	792	WP_011285534.1	ribonuclease HII	-
ACB333_RS04475 (ACB333_04480)	dprA	892702..893538 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
ACB333_RS04480 (ACB333_04485)	topA	893645..895774 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
ACB333_RS04485 (ACB333_04490)	-	895849..896731 (-)	883	Protein_846	LysR family transcriptional regulator	-
ACB333_RS04490 (ACB333_04495)	-	896744..897289 (+)	546	Protein_847	PTS sugar transporter subunit IIC	-
ACB333_RS04495 (ACB333_04500)	-	897304..898296 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=1037363 ACB333_RS04475 WP_010922314.1 892702..893538(+) (dprA) [Streptococcus pyogenes strain Isolate 20]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037363 ACB333_RS04475 WP_010922314.1 892702..893538(+) (dprA) [Streptococcus pyogenes strain Isolate 20]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367