Detailed information NTG1037198

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB342_RS04540
• Genome accession: NZ_CP167007
• Coordinates: 898703..899539 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 24
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 893703..904539

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB342_RS04510 (ACB342_04515)	-	894257..894625 (+)	369	WP_010922310.1	hypothetical protein	-
ACB342_RS04515 (ACB342_04520)	-	894675..895586 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
ACB342_RS04520 (ACB342_04525)	-	895703..896353 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB342_RS04525 (ACB342_04530)	-	896350..896790 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB342_RS04530 (ACB342_04535)	ylqF	897009..897857 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
ACB342_RS04535 (ACB342_04540)	-	897847..898638 (+)	792	WP_011285534.1	ribonuclease HII	-
ACB342_RS04540 (ACB342_04545)	dprA	898703..899539 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
ACB342_RS04545 (ACB342_04550)	topA	899646..901775 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
ACB342_RS04550 (ACB342_04555)	-	901850..902732 (-)	883	Protein_846	LysR family transcriptional regulator	-
ACB342_RS04555 (ACB342_04560)	-	902745..903290 (+)	546	Protein_847	PTS sugar transporter subunit IIC	-
ACB342_RS04560 (ACB342_04565)	-	903305..904297 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=1037198 ACB342_RS04540 WP_010922314.1 898703..899539(+) (dprA) [Streptococcus pyogenes strain Isolate 24]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037198 ACB342_RS04540 WP_010922314.1 898703..899539(+) (dprA) [Streptococcus pyogenes strain Isolate 24]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367