Detailed information NTG1037151

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB360_RS04355
• Genome accession: NZ_CP167006
• Coordinates: 870644..871480 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 26
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 865644..876480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB360_RS04325 (ACB360_04325)	-	866126..866566 (+)	441	WP_024623381.1	hypothetical protein	-
ACB360_RS04330 (ACB360_04330)	-	866616..867527 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ACB360_RS04335 (ACB360_04335)	-	867644..868294 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB360_RS04340 (ACB360_04340)	-	868291..868731 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB360_RS04345 (ACB360_04345)	ylqF	868950..869798 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
ACB360_RS04350 (ACB360_04350)	-	869788..870579 (+)	792	WP_002989771.1	ribonuclease HII	-
ACB360_RS04355 (ACB360_04355)	dprA	870644..871480 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
ACB360_RS04360 (ACB360_04360)	topA	871587..873716 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
ACB360_RS04365 (ACB360_04365)	-	873791..874648 (-)	858	Protein_818	LysR family transcriptional regulator	-
ACB360_RS04370 (ACB360_04370)	-	874688..875254 (+)	567	Protein_819	PTS sugar transporter subunit IIC	-
ACB360_RS04375 (ACB360_04375)	-	875269..876261 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1037151 ACB360_RS04355 WP_002989770.1 870644..871480(+) (dprA) [Streptococcus pyogenes strain Isolate 26]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037151 ACB360_RS04355 WP_002989770.1 870644..871480(+) (dprA) [Streptococcus pyogenes strain Isolate 26]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367