Detailed information NTG1037043

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB354_RS04725
• Genome accession: NZ_CP167004
• Coordinates: 874562..875398 (+)
• Length: 278 a.a.
• NCBI ID: WP_011184519.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 28
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 869562..880398

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB354_RS04695 (ACB354_04695)	-	870050..870484 (+)	435	WP_011017767.1	hypothetical protein	-
ACB354_RS04700 (ACB354_04700)	-	870534..871445 (-)	912	WP_011184516.1	diacylglycerol kinase family protein	-
ACB354_RS04705 (ACB354_04705)	-	871562..872212 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB354_RS04710 (ACB354_04710)	-	872209..872649 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ACB354_RS04715 (ACB354_04715)	ylqF	872868..873716 (+)	849	WP_011184517.1	ribosome biogenesis GTPase YlqF	-
ACB354_RS04720 (ACB354_04720)	-	873706..874497 (+)	792	WP_011184518.1	ribonuclease HII	-
ACB354_RS04725 (ACB354_04725)	dprA	874562..875398 (+)	837	WP_011184519.1	DNA-processing protein DprA	Machinery gene
ACB354_RS04730 (ACB354_04730)	topA	875505..877634 (+)	2130	WP_011184520.1	type I DNA topoisomerase	-
ACB354_RS04735 (ACB354_04735)	trmFO	877769..879115 (+)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31136.17 Da
• Isoelectric Point: 9.2335

>NTDB_id=1037043 ACB354_RS04725 WP_011184519.1 874562..875398(+) (dprA) [Streptococcus pyogenes strain Isolate 28]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMYILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1037043 ACB354_RS04725 WP_011184519.1 874562..875398(+) (dprA) [Streptococcus pyogenes strain Isolate 28]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCTATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGTATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363