Detailed information NTG1036760

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB350_RS04970
• Genome accession: NZ_CP166999
• Coordinates: 945576..946412 (+)
• Length: 278 a.a.
• NCBI ID: WP_030127252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 34
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 940576..951412

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB350_RS04940 (ACB350_04940)	-	941130..941498 (+)	369	WP_129304101.1	hypothetical protein	-
ACB350_RS04945 (ACB350_04945)	-	941548..942459 (-)	912	WP_011184516.1	diacylglycerol kinase family protein	-
ACB350_RS04950 (ACB350_04950)	-	942576..943226 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB350_RS04955 (ACB350_04955)	-	943223..943663 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ACB350_RS04960 (ACB350_04960)	ylqF	943882..944730 (+)	849	WP_030127254.1	ribosome biogenesis GTPase YlqF	-
ACB350_RS04965 (ACB350_04965)	-	944720..945511 (+)	792	WP_030127253.1	ribonuclease HII	-
ACB350_RS04970 (ACB350_04970)	dprA	945576..946412 (+)	837	WP_030127252.1	DNA-processing protein DprA	Machinery gene
ACB350_RS04975 (ACB350_04975)	topA	946519..948648 (+)	2130	WP_030127251.1	type I DNA topoisomerase	-
ACB350_RS04980 (ACB350_04980)	trmFO	948783..950129 (+)	1347	WP_030127250.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31087.09 Da
• Isoelectric Point: 9.2565

>NTDB_id=1036760 ACB350_RS04970 WP_030127252.1 945576..946412(+) (dprA) [Streptococcus pyogenes strain Isolate 34]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSNTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1036760 ACB350_RS04970 WP_030127252.1 945576..946412(+) (dprA) [Streptococcus pyogenes strain Isolate 34]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCAATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367