Detailed information NTG1036707

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACB356_RS04680
• Genome accession: NZ_CP166998
• Coordinates: 916422..917258 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 35
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 911422..922258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB356_RS04650 (ACB356_04650)	-	911904..912344 (+)	441	WP_024623381.1	hypothetical protein	-
ACB356_RS04655 (ACB356_04655)	-	912394..913305 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ACB356_RS04660 (ACB356_04660)	-	913422..914072 (-)	651	WP_002984629.1	hemolysin III family protein	-
ACB356_RS04665 (ACB356_04665)	-	914069..914509 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ACB356_RS04670 (ACB356_04670)	ylqF	914728..915576 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
ACB356_RS04675 (ACB356_04675)	-	915566..916357 (+)	792	WP_002989771.1	ribonuclease HII	-
ACB356_RS04680 (ACB356_04680)	dprA	916422..917258 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
ACB356_RS04685 (ACB356_04685)	topA	917365..919494 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
ACB356_RS04690 (ACB356_04690)	-	919569..920426 (-)	858	Protein_876	LysR family transcriptional regulator	-
ACB356_RS04695 (ACB356_04695)	-	920466..921032 (+)	567	Protein_877	PTS sugar transporter subunit IIC	-
ACB356_RS04700 (ACB356_04700)	-	921047..922039 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1036707 ACB356_RS04680 WP_002989770.1 916422..917258(+) (dprA) [Streptococcus pyogenes strain Isolate 35]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1036707 ACB356_RS04680 WP_002989770.1 916422..917258(+) (dprA) [Streptococcus pyogenes strain Isolate 35]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367