Detailed information NTG1036431

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: ACA346_RS04950
• Genome accession: NZ_CP166970
• Coordinates: 971986..972657 (+)
• Length: 223 a.a.
• NCBI ID: WP_418127408.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain NX1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 966986..977657

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACA346_RS04915 (ACA346_04915)	-	967228..969093 (+)	1866	WP_418127405.1	DUF7657 domain-containing protein	-
ACA346_RS04920 (ACA346_04920)	-	969303..970655 (-)	1353	WP_418126723.1	IS66-like element short variant transposase	-
ACA346_RS04925 (ACA346_04925)	-	970609..970815 (-)	207	WP_099390666.1	transposase	-
ACA346_RS04930 (ACA346_04930)	tnpB	970867..971217 (-)	351	WP_014295152.1	IS66 family insertion sequence element accessory protein TnpB	-
ACA346_RS04935 (ACA346_04935)	-	971198..971383 (-)	186	WP_418126722.1	hypothetical protein	-
ACA346_RS04940 (ACA346_04940)	-	971512..971640 (+)	129	WP_418127406.1	hypothetical protein	-
ACA346_RS04945 (ACA346_04945)	-	971695..971889 (+)	195	WP_418127407.1	hypothetical protein	-
ACA346_RS04950 (ACA346_04950)	ciaR	971986..972657 (+)	672	WP_418127408.1	response regulator transcription factor	Regulator
ACA346_RS04955 (ACA346_04955)	ciaH	972650..974023 (+)	1374	WP_418127409.1	sensor histidine kinase	Regulator
ACA346_RS04960 (ACA346_04960)	-	974110..975327 (+)	1218	WP_418127411.1	transglutaminase domain-containing protein	-
ACA346_RS04965 (ACA346_04965)	rpsT	975361..975609 (-)	249	WP_277843602.1	30S ribosomal protein S20	-
ACA346_RS04970 (ACA346_04970)	coaA	975668..976588 (-)	921	WP_418127412.1	type I pantothenate kinase	-
ACA346_RS04975 (ACA346_04975)	-	976664..977254 (+)	591	WP_217375057.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25226.83 Da
• Isoelectric Point: 4.2408

>NTDB_id=1036431 ACA346_RS04950 WP_418127408.1 971986..972657(+) (ciaR) [Streptococcus parasuis strain NX1]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPDKDGFQVLRELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTIDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide

• Length: 672 bp

>NTDB_id=1036431 ACA346_RS04950 WP_418127408.1 971986..972657(+) (ciaR) [Streptococcus parasuis strain NX1]
ATGATTAAGATACTGTTGGTAGAAGACGATTTAAGCCTTTCTAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGATTTAATTCTTTTAGATTTAATGT
TACCTGATAAAGATGGTTTTCAAGTATTAAGAGAATTGCGTGAAAAAGGGGTCTCAACTCCTGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACGTACGGAGATGTTACTA
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAATTCGACTTGTTGGTATAT
TTCTTACAGAACCAGAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAAGTTTACGTATCGAAAGTAAGGAAAAAATTGAAAGGAACTGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	87.892	100	0.879
ciaR	Streptococcus pneumoniae Rx1	87.444	100	0.874
ciaR	Streptococcus pneumoniae D39	87.444	100	0.874
ciaR	Streptococcus pneumoniae R6	87.444	100	0.874
ciaR	Streptococcus pneumoniae TIGR4	87.444	100	0.874
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	34.615	100	0.363