Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACA346_RS04955 Genome accession   NZ_CP166970
Coordinates   972650..974023 (+) Length   457 a.a.
NCBI ID   WP_418127409.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 967650..979023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS04920 (ACA346_04920) - 969303..970655 (-) 1353 WP_418126723.1 IS66-like element short variant transposase -
  ACA346_RS04925 (ACA346_04925) - 970609..970815 (-) 207 WP_099390666.1 transposase -
  ACA346_RS04930 (ACA346_04930) tnpB 970867..971217 (-) 351 WP_014295152.1 IS66 family insertion sequence element accessory protein TnpB -
  ACA346_RS04935 (ACA346_04935) - 971198..971383 (-) 186 WP_418126722.1 hypothetical protein -
  ACA346_RS04940 (ACA346_04940) - 971512..971640 (+) 129 WP_418127406.1 hypothetical protein -
  ACA346_RS04945 (ACA346_04945) - 971695..971889 (+) 195 WP_418127407.1 hypothetical protein -
  ACA346_RS04950 (ACA346_04950) ciaR 971986..972657 (+) 672 WP_418127408.1 response regulator transcription factor Regulator
  ACA346_RS04955 (ACA346_04955) ciaH 972650..974023 (+) 1374 WP_418127409.1 sensor histidine kinase Regulator
  ACA346_RS04960 (ACA346_04960) - 974110..975327 (+) 1218 WP_418127411.1 transglutaminase domain-containing protein -
  ACA346_RS04965 (ACA346_04965) rpsT 975361..975609 (-) 249 WP_277843602.1 30S ribosomal protein S20 -
  ACA346_RS04970 (ACA346_04970) coaA 975668..976588 (-) 921 WP_418127412.1 type I pantothenate kinase -
  ACA346_RS04975 (ACA346_04975) - 976664..977254 (+) 591 WP_217375057.1 class I SAM-dependent methyltransferase -
  ACA346_RS04980 (ACA346_04980) - 977251..978528 (+) 1278 WP_418127413.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51526.66 Da        Isoelectric Point: 5.1151

>NTDB_id=1036432 ACA346_RS04955 WP_418127409.1 972650..974023(+) (ciaH) [Streptococcus parasuis strain NX1]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNIADESDSAESNSDTQNSPKNQKDDQLKLGYNTHVLLYSKDGQVVNPDNFTGLSDLSLDKKNLGEIKEVTVDSTFGSSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FENYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEDDGAIQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=1036432 ACA346_RS04955 WP_418127409.1 972650..974023(+) (ciaH) [Streptococcus parasuis strain NX1]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCCTTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTGCTGATGAAAGTGATTCTGCTGAATCTAATTCAGATACACAAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTGCTTTATTCAAAAGATGGTCAAGTAGTTAACCCTGATAACTTTACCGGTT
TGTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGTAACGGTTGATTCTACATTCGGGAGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTCTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTGAGAATTACATGATGATTGCAGATGAGAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGATGATGGCGCTATAC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGTGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCCTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCGAGATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae D39

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae R6

51.096

99.781

0.51
  ciaH Streptococcus pneumoniae TIGR4

51.096

99.781

0.51
  ciaH Streptococcus mutans UA159

50.11

99.125

0.497

Multiple sequence alignment