Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACA346_RS00320 Genome accession   NZ_CP166970
Coordinates   55519..56871 (+) Length   450 a.a.
NCBI ID   WP_418126902.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 50519..61871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS00310 (ACA346_00310) - 51590..52858 (+) 1269 WP_418126900.1 MerR family transcriptional regulator -
  ACA346_RS00315 (ACA346_00315) comA 53354..55507 (+) 2154 WP_418126901.1 peptide cleavage/export ABC transporter ComA Regulator
  ACA346_RS00320 (ACA346_00320) comB 55519..56871 (+) 1353 WP_418126902.1 bacteriocin secretion accessory protein Regulator
  ACA346_RS00325 (ACA346_00325) - 57260..57439 (+) 180 WP_024392853.1 hypothetical protein -
  ACA346_RS00330 (ACA346_00330) - 57440..57640 (+) 201 WP_289646201.1 hypothetical protein -
  ACA346_RS00335 (ACA346_00335) - 57657..57848 (+) 192 WP_024397557.1 hypothetical protein -
  ACA346_RS00340 (ACA346_00340) - 58337..59593 (+) 1257 WP_418126903.1 ISL3 family transposase -
  ACA346_RS00345 (ACA346_00345) - 59632..60501 (-) 870 WP_418126904.1 cysteine ABC transporter substrate-binding protein -
  ACA346_RS00350 (ACA346_00350) - 60514..61260 (-) 747 WP_217374488.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50771.45 Da        Isoelectric Point: 4.8877

>NTDB_id=1036410 ACA346_RS00320 WP_418126902.1 55519..56871(+) (comB) [Streptococcus parasuis strain NX1]
MDHHLLESAEFYNRRYHNAASRVIIPSCILFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQAAKQSQLELEKVMHQTEKALADYRELKRAIQSDGVIDEENVGYSIYAQYQLAQSEDAVASQESFVAQIDNQI
SQVETQLASYKLQYAGAGVQQSYTNSLDSQSASLKAQYLTKVGQEMTMLSSQLRDLEATLTVQKQAMDKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1036410 ACA346_RS00320 WP_418126902.1 55519..56871(+) (comB) [Streptococcus parasuis strain NX1]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAATAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTATATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCTAAAAAAGAAATGACCATTTCAACAAGAGCAACCGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTGAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTGGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCTGCAAAACAATCACAATTGGAATTGGAAAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAACGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGTTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCGTCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCGGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCATGTTGTCTTCTCAATTAA
GAGACCTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGATAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGGGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTCTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

49.666

99.778

0.496
  comB Streptococcus pneumoniae D39

47.333

100

0.473
  comB Streptococcus pneumoniae R6

47.333

100

0.473
  comB Streptococcus pneumoniae Rx1

47.333

100

0.473
  comB Streptococcus pneumoniae TIGR4

46.889

100

0.469
  comB Streptococcus mitis NCTC 12261

46

100

0.46
  comB Streptococcus mitis SK321

45.778

100

0.458

Multiple sequence alignment