Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACA346_RS00315 Genome accession   NZ_CP166970
Coordinates   53354..55507 (+) Length   717 a.a.
NCBI ID   WP_418126901.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 48354..60507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS00300 (ACA346_00300) - 49019..49765 (+) 747 WP_418126898.1 hypothetical protein -
  ACA346_RS00305 (ACA346_00305) - 49770..51482 (+) 1713 WP_418126899.1 ABC transporter ATP-binding protein -
  ACA346_RS00310 (ACA346_00310) - 51590..52858 (+) 1269 WP_418126900.1 MerR family transcriptional regulator -
  ACA346_RS00315 (ACA346_00315) comA 53354..55507 (+) 2154 WP_418126901.1 peptide cleavage/export ABC transporter ComA Regulator
  ACA346_RS00320 (ACA346_00320) comB 55519..56871 (+) 1353 WP_418126902.1 bacteriocin secretion accessory protein Regulator
  ACA346_RS00325 (ACA346_00325) - 57260..57439 (+) 180 WP_024392853.1 hypothetical protein -
  ACA346_RS00330 (ACA346_00330) - 57440..57640 (+) 201 WP_289646201.1 hypothetical protein -
  ACA346_RS00335 (ACA346_00335) - 57657..57848 (+) 192 WP_024397557.1 hypothetical protein -
  ACA346_RS00340 (ACA346_00340) - 58337..59593 (+) 1257 WP_418126903.1 ISL3 family transposase -
  ACA346_RS00345 (ACA346_00345) - 59632..60501 (-) 870 WP_418126904.1 cysteine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81048.34 Da        Isoelectric Point: 7.1946

>NTDB_id=1036409 ACA346_RS00315 WP_418126901.1 53354..55507(+) (comA) [Streptococcus parasuis strain NX1]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMAPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTL
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDQKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYGPYKGEIRLNNVNINQIDKQTLRQHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1036409 ACA346_RS00315 WP_418126901.1 53354..55507(+) (comA) [Streptococcus parasuis strain NX1]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTAGATACACGAGACTGTGGTGTAGCAGCGCTTGCTATGATCTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCTCATGTGGTAAAAGATGGCACGTTACTACATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGGCTCCCAAACCGGAATATCAACCACATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTCGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTCCCAAATCAGATGAAAACAACCTTAGGTGTCATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATGCCCAAGAGTATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATGTTTTTCATCTACCAATGTCATTTTTTGCTACCCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTATTGGCATTGCCAATCTATACTCTA
ATCATTTTTGCGTTTATGAAGCCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
TATTGAAGATATCAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCAATTCTTTGGTTAGGAGCCTGTCTTGTTATGGATCAGAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACCTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAACTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGGCCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCAGCATATT
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATCTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
AATTGACTTCTGATGGAGCTGGAATCTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACTCTAATTTTTATTGCACATCGGTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGCTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.637

100

0.796
  comA Streptococcus pneumoniae D39

79.637

100

0.796
  comA Streptococcus pneumoniae R6

79.637

100

0.796
  comA Streptococcus mitis NCTC 12261

79.498

100

0.795
  comA Streptococcus pneumoniae TIGR4

79.358

100

0.794
  comA Streptococcus mitis SK321

79.358

100

0.794
  comA Streptococcus gordonii str. Challis substr. CH1

77.406

100

0.774
  comA/nlmT Streptococcus mutans UA159

63.598

100

0.636

Multiple sequence alignment