Detailed information NTG1033133

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: JNUCC21_RS13570
• Genome accession: NZ_CP166019
• Coordinates: 2719519..2720133 (-)
• Length: 204 a.a.
• NCBI ID: WP_369878216.1
• Uniprot ID: -
• Organism: Bacillus sp. JNUCC-21
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2714519..2725133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JNUCC21_RS13540 (JNUCC21_13570)	rpsT	2714822..2715088 (+)	267	WP_003152876.1	30S ribosomal protein S20	-
JNUCC21_RS13545 (JNUCC21_13575)	holA	2715105..2716146 (-)	1042	Protein_2624	DNA polymerase III subunit delta	-
JNUCC21_RS13550 (JNUCC21_13580)	-	2716186..2716337 (-)	152	Protein_2625	hypothetical protein	-
JNUCC21_RS13555 (JNUCC21_13585)	-	2716378..2716512 (+)	135	WP_003152870.1	YqzM family protein	-
JNUCC21_RS13560 (JNUCC21_13590)	comEC	2716531..2718882 (-)	2352	WP_369878215.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
JNUCC21_RS13565 (JNUCC21_13595)	-	2718883..2719452 (-)	570	WP_003152868.1	ComE operon protein 2	-
JNUCC21_RS13570 (JNUCC21_13600)	comEA	2719519..2720133 (-)	615	WP_369878216.1	helix-hairpin-helix domain-containing protein	Machinery gene
JNUCC21_RS13575 (JNUCC21_13605)	comER	2720192..2721013 (+)	822	WP_015240246.1	late competence protein ComER	-
JNUCC21_RS13580 (JNUCC21_13610)	-	2721082..2721819 (-)	738	WP_015417856.1	class I SAM-dependent methyltransferase	-
JNUCC21_RS13585 (JNUCC21_13615)	rsfS	2721816..2722172 (-)	357	WP_007408260.1	ribosome silencing factor	-
JNUCC21_RS13590 (JNUCC21_13620)	yqeK	2722190..2722750 (-)	561	WP_014418422.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
JNUCC21_RS13595 (JNUCC21_13625)	-	2722740..2723309 (-)	570	WP_007408258.1	nicotinate-nucleotide adenylyltransferase	-
JNUCC21_RS13600 (JNUCC21_13630)	yhbY	2723320..2723610 (-)	291	WP_007408257.1	ribosome assembly RNA-binding protein YhbY	-
JNUCC21_RS13605 (JNUCC21_13635)	aroE	2723604..2724446 (-)	843	WP_059368084.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22153.26 Da
• Isoelectric Point: 6.4858

>NTDB_id=1033133 JNUCC21_RS13570 WP_369878216.1 2719519..2720133(-) (comEA) [Bacillus sp. JNUCC-21]
MTKAMMTERLRRNLKILGACLAAGAAFICIWLFRSDKEEPVKQQSVLGQTASTSVADKKDTAADKIMIDVKGAVRNPGVY
EMKAGDRVTQAIEKAGGLKKKADELNVNLAEQLQDGTIVYIPSEGEEENRPKTAAGEKENAAVNINTASLDELQAISGVG
QKKAEAIIAYREENGRFQTAEDLMNVSGFGEKSFERIKTSITVK

Nucleotide

• Length: 615 bp

>NTDB_id=1033133 JNUCC21_RS13570 WP_369878216.1 2719519..2720133(-) (comEA) [Bacillus sp. JNUCC-21]
ATGACGAAAGCGATGATGACGGAGCGGCTGCGGCGGAACCTGAAAATTCTGGGCGCTTGTCTTGCGGCAGGGGCGGCTTT
TATCTGTATTTGGCTGTTTCGTTCTGACAAGGAAGAGCCGGTCAAACAGCAGTCCGTGCTCGGCCAAACAGCCTCAACAT
CCGTCGCGGACAAAAAAGACACCGCAGCCGACAAGATTATGATTGATGTGAAAGGCGCGGTCCGAAATCCCGGCGTATAT
GAAATGAAAGCGGGAGACAGGGTGACGCAAGCCATTGAAAAAGCCGGCGGCCTGAAGAAAAAGGCGGATGAATTGAATGT
TAATTTAGCAGAGCAGCTGCAGGACGGGACGATTGTTTATATTCCGAGTGAAGGCGAAGAGGAGAATCGCCCGAAAACAG
CGGCGGGTGAAAAGGAGAATGCAGCTGTCAATATCAATACGGCATCTCTGGACGAACTTCAGGCAATTTCCGGGGTGGGG
CAGAAAAAAGCGGAAGCGATTATCGCCTACCGAGAAGAAAACGGACGGTTTCAGACTGCTGAAGATTTGATGAATGTATC
AGGCTTTGGAGAGAAGTCATTTGAGCGGATAAAAACTTCCATTACGGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (141-202)

• SLBB domain (SLBB) (68-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	58.974	95.588	0.564
comEA	Latilactobacillus sakei subsp. sakei 23K	33.48	100	0.373
comEA/celA/cilE	Streptococcus mitis NCTC 12261	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae Rx1	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae D39	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae R6	35.545	100	0.368
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	35.545	100	0.368
comEA/celA/cilE	Streptococcus mitis SK321	35.071	100	0.363