Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   AB4X21_RS07445 Genome accession   NZ_CP163380
Coordinates   1457053..1457754 (-) Length   233 a.a.
NCBI ID   WP_003005102.1    Uniprot ID   -
Organism   Streptococcus sp. CP1998     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452053..1462754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS07420 (AB4X21_07420) rnc 1452637..1453338 (-) 702 WP_320910529.1 ribonuclease III -
  AB4X21_RS07425 (AB4X21_07425) - 1453672..1454133 (+) 462 WP_320910528.1 hypothetical protein -
  AB4X21_RS07430 (AB4X21_07430) - 1454385..1454771 (-) 387 WP_320910527.1 YbaN family protein -
  AB4X21_RS07435 (AB4X21_07435) vicX 1454891..1455700 (-) 810 WP_369087744.1 MBL fold metallo-hydrolase Regulator
  AB4X21_RS07440 (AB4X21_07440) micB 1455708..1457060 (-) 1353 WP_003005638.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AB4X21_RS07445 (AB4X21_07445) micA 1457053..1457754 (-) 702 WP_003005102.1 response regulator YycF Regulator
  AB4X21_RS07450 (AB4X21_07450) - 1458256..1459305 (+) 1050 WP_320910525.1 DUF389 domain-containing protein -
  AB4X21_RS07455 (AB4X21_07455) thrS 1459517..1461460 (-) 1944 WP_320910524.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26782.59 Da        Isoelectric Point: 4.7296

>NTDB_id=1029440 AB4X21_RS07445 WP_003005102.1 1457053..1457754(-) (micA) [Streptococcus sp. CP1998]
MKRILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFSAENPDVIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQFEKDADTEIVIGDLHILPDAFLVRKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1029440 AB4X21_RS07445 WP_003005102.1 1457053..1457754(-) (micA) [Streptococcus sp. CP1998]
ATGAAAAGAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAGGGATATGA
AGTTTTAACGGCCTTTGATGGGCGGGAAGCTTTAGAAGTCTTTTCAGCTGAAAACCCAGATGTTATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGCTTGGAAGTGGCGCGGACGATTCGTAAGACCAGCAATGTGCCCATCATTGTCCTATCTGCT
AAGGATACGGAATTTGATAAGGTCATCGGGCTTGAAATCGGGGCGGATGACTATGTGACCAAACCTTTCTCTAATCGGGA
ATTACAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCGGAGTTTGCGGCTGATCCTCAGTTTGAAAAAGATGCCGATACAG
AAATTGTCATTGGCGATCTTCACATTCTTCCAGACGCTTTCTTGGTTCGAAAAGGCAACAAAGAATTGGACTTGACTCAT
CGCGAGTTTGAGTTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAACATCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACGGTGGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

100

0.815
  vicR Streptococcus mutans UA159

77.872

100

0.785
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

98.283

0.451
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.826

98.712

0.373

Multiple sequence alignment