Detailed information NTG1020964

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ABZ559_RS12420
• Genome accession: NZ_CP160400
• Coordinates: 2467568..2468473 (-)
• Length: 301 a.a.
• NCBI ID: WP_277291088.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY19097
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2462568..2473473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABZ559_RS12400 (ABZ559_12400)	-	2463204..2464991 (-)	1788	WP_367006623.1	acyltransferase family protein	-
ABZ559_RS12405 (ABZ559_12405)	-	2464988..2465368 (-)	381	WP_018375427.1	membrane protein	-
ABZ559_RS12410 (ABZ559_12410)	-	2465386..2465814 (-)	429	WP_273402539.1	low molecular weight protein-tyrosine-phosphatase	-
ABZ559_RS12415 (ABZ559_12415)	ruvB	2466102..2467103 (-)	1002	WP_367006625.1	Holliday junction branch migration DNA helicase RuvB	-
ABZ559_RS12420 (ABZ559_12420)	comR	2467568..2468473 (-)	906	WP_277291088.1	helix-turn-helix domain-containing protein	Regulator
ABZ559_RS12425 (ABZ559_12425)	-	2468550..2468711 (-)	162	Protein_2426	helix-turn-helix transcriptional regulator	-
ABZ559_RS12430 (ABZ559_12430)	comR	2468753..2469664 (-)	912	WP_277291087.1	helix-turn-helix domain-containing protein	Regulator
ABZ559_RS12435 (ABZ559_12435)	purB	2469881..2471179 (-)	1299	WP_367006627.1	adenylosuccinate lyase	-
ABZ559_RS12440 (ABZ559_12440)	-	2471401..2471550 (-)	150	WP_367006629.1	hypothetical protein	-
ABZ559_RS12445 (ABZ559_12445)	-	2471543..2472586 (-)	1044	WP_367006630.1	hypothetical protein	-
ABZ559_RS12450 (ABZ559_12450)	-	2472655..2473056 (-)	402	Protein_2431	SRPBCC family protein	-
ABZ559_RS12455 (ABZ559_12455)	-	2473137..2473283 (-)	147	Protein_2432	CPBP family intramembrane glutamate endopeptidase	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35308.71 Da
• Isoelectric Point: 4.6185

>NTDB_id=1020964 ABZ559_RS12420 WP_277291088.1 2467568..2468473(-) (comR) [Streptococcus sp. ZY19097]
MINQFGEKVRYLREQREITREEFCGDETELSVRQLARIETGSLPNLSKAQFIASRLGVQLGELTDEKSLELPKRYKELKY
LILRTPLYAEPERIKTREEQLDEVSEVFYDTLPEYEQLVIDCLQAKLDIHMSNNISFGLGIIDDYFEQITKKNNYSLNDL
VVIDIYFMSIISEIKKGESASLKDFNKLVNNLIEQRDNFNIETLFVLNNLLIHACGVYLEIANIEKIEMLIKICERIMSK
IQDFQKSPILNMIEWKLSLQLLKDKKRAEACYSKALLFSNIMEDEYLETKLQEEWQKDCAT

Nucleotide

• Length: 906 bp

>NTDB_id=1020964 ABZ559_RS12420 WP_277291088.1 2467568..2468473(-) (comR) [Streptococcus sp. ZY19097]
ATGATAAACCAATTTGGAGAAAAAGTTAGGTATCTAAGAGAGCAAAGAGAAATTACGCGAGAAGAATTTTGCGGAGATGA
AACCGAACTCTCAGTTAGACAATTAGCCAGAATTGAGACGGGTTCCCTACCTAATTTATCAAAAGCACAGTTCATTGCAA
GTCGATTAGGAGTTCAACTTGGAGAGTTGACAGATGAAAAAAGTTTAGAGCTTCCAAAGCGATATAAAGAACTAAAGTAT
CTGATTTTGAGGACTCCTTTGTACGCGGAACCTGAAAGAATTAAAACACGTGAGGAACAACTTGATGAAGTTTCAGAAGT
ATTTTATGACACTCTTCCAGAGTATGAGCAATTGGTTATTGATTGTCTGCAAGCAAAGCTTGATATACATATGAGTAATA
ATATTTCCTTTGGTTTAGGTATTATAGACGATTATTTTGAACAAATAACTAAAAAAAATAATTATAGTTTAAATGATTTA
GTTGTTATAGACATTTATTTTATGAGCATTATATCGGAAATTAAAAAAGGGGAGTCTGCTAGTCTTAAAGACTTCAATAA
ACTTGTTAATAATTTAATTGAACAGAGAGACAACTTCAATATAGAAACATTATTTGTTTTAAATAATTTACTTATACATG
CTTGTGGGGTCTATCTGGAAATTGCTAATATTGAAAAAATTGAGATGCTTATAAAAATTTGTGAGCGTATCATGTCTAAG
ATTCAAGACTTTCAAAAATCTCCTATTTTGAATATGATTGAATGGAAACTAAGTTTACAACTATTAAAAGATAAGAAACG
AGCAGAAGCTTGTTATAGCAAAGCGTTGCTTTTTTCTAATATAATGGAAGATGAATATTTAGAGACAAAATTACAAGAAG
AATGGCAAAAAGATTGTGCAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-63)

• ComR tetratricopeptide (ComR_TPR) (72-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.389	95.681	0.492
comR	Streptococcus mutans UA159	47	99.668	0.468
comR	Streptococcus pyogenes MGAS8232	46.358	100	0.465
comR	Streptococcus pyogenes MGAS315	43.813	99.336	0.435
comR	Streptococcus suis P1/7	39.527	98.339	0.389
comR	Streptococcus suis 05ZYH33	39.527	98.339	0.389
comR	Streptococcus suis D9	36.455	99.336	0.362