Detailed information NTG1017332

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ABHI20_RS04970
• Genome accession: NZ_CP160045
• Coordinates: 956159..956995 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes M1 GAS strain SF370
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 951159..961995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABHI20_RS04940 (ABHI20_04940)	-	951713..952081 (+)	369	WP_010922310.1	hypothetical protein	-
ABHI20_RS04945 (ABHI20_04945)	-	952131..953042 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
ABHI20_RS04950 (ABHI20_04950)	-	953159..953809 (-)	651	WP_002984629.1	hemolysin III family protein	-
ABHI20_RS04955 (ABHI20_04955)	-	953806..954246 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ABHI20_RS04960 (ABHI20_04960)	ylqF	954465..955313 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
ABHI20_RS04965 (ABHI20_04965)	-	955303..956094 (+)	792	WP_010922313.1	ribonuclease HII	-
ABHI20_RS04970 (ABHI20_04970)	dprA	956159..956995 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
ABHI20_RS04975 (ABHI20_04975)	topA	957102..959231 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
ABHI20_RS04980 (ABHI20_04980)	-	959306..960188 (-)	883	Protein_934	LysR family transcriptional regulator	-
ABHI20_RS04985 (ABHI20_04985)	-	960201..960746 (+)	546	Protein_935	PTS sugar transporter subunit IIC	-
ABHI20_RS04990 (ABHI20_04990)	-	960761..961753 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=1017332 ABHI20_RS04970 WP_010922314.1 956159..956995(+) (dprA) [Streptococcus pyogenes M1 GAS strain SF370]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1017332 ABHI20_RS04970 WP_010922314.1 956159..956995(+) (dprA) [Streptococcus pyogenes M1 GAS strain SF370]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367