Detailed information NTG1011632

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H1W94_RS01475
• Genome accession: NZ_LR822041
• Coordinates: 271177..272076 (+)
• Length: 299 a.a.
• NCBI ID: WP_156703476.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1122
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 266177..277076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W94_RS01455 (STHERMO_0294)	-	267603..268556 (-)	954	WP_041826943.1	IS30 family transposase	-
H1W94_RS01460 (STHERMO_0295)	-	268921..269460 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H1W94_RS01465 (STHERMO_0296)	-	269772..270329 (+)	558	WP_002949523.1	ECF transporter S component	-
H1W94_RS01470 (STHERMO_0297)	-	270332..270982 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
H1W94_RS01475 (STHERMO_0298)	comR	271177..272076 (+)	900	WP_156703476.1	helix-turn-helix domain-containing protein	Regulator
H1W94_RS09595	-	272315..273493 (+)	1179	Protein_244	ABC transporter transmembrane domain-containing protein	-
H1W94_RS01495 (STHERMO_0303)	-	273779..274347 (+)	569	Protein_245	ATP-binding cassette domain-containing protein	-
H1W94_RS01500 (STHERMO_0304)	-	274455..274766 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
H1W94_RS09600 (STHERMO_0305)	-	274734..275018 (-)	285	WP_231108755.1	hypothetical protein	-
H1W94_RS09605 (STHERMO_0308)	-	275784..276155 (-)	372	WP_231108754.1	hypothetical protein	-
H1W94_RS01510 (STHERMO_0309)	-	276560..277075 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35345.85 Da
• Isoelectric Point: 5.1073

>NTDB_id=1011632 H1W94_RS01475 WP_156703476.1 271177..272076(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_1122]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAVENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1011632 H1W94_RS01475 WP_156703476.1 271177..272076(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_1122]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGTAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	98.662	100	0.987
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421