Detailed information NTG1010368

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H1X63_RS01605
• Genome accession: NZ_LR822027
• Coordinates: 293674..294573 (+)
• Length: 299 a.a.
• NCBI ID: WP_084825763.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_998
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 288674..299573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X63_RS01585 (STHERMO_0290)	-	290098..290637 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H1X63_RS01590 (STHERMO_0291)	-	290948..291505 (+)	558	WP_179972601.1	ECF transporter S component	-
H1X63_RS01595 (STHERMO_0292)	-	291508..292158 (+)	651	WP_179972602.1	phosphatase PAP2 family protein	-
H1X63_RS01600 (STHERMO_0294)	-	292328..293503 (-)	1176	WP_179972979.1	IS256-like element IS1191 family transposase	-
H1X63_RS01605 (STHERMO_0295)	comR	293674..294573 (+)	900	WP_084825763.1	helix-turn-helix domain-containing protein	Regulator
H1X63_RS10415	-	294748..296220 (+)	1473	Protein_263	peptide cleavage/export ABC transporter	-
H1X63_RS01620 (STHERMO_0299)	comA	296275..296844 (+)	570	WP_232086885.1	ATP-binding cassette domain-containing protein	Regulator
H1X63_RS01625 (STHERMO_0300)	-	296971..297282 (+)	312	WP_095559231.1	DUF805 domain-containing protein	-
H1X63_RS10420 (STHERMO_0301)	-	297364..297531 (-)	168	WP_232086209.1	hypothetical protein	-
H1X63_RS11065	-	297503..297850 (-)	348	WP_232086208.1	DUF4153 domain-containing protein	-
H1X63_RS10425 (STHERMO_0303)	-	297775..298077 (-)	303	WP_232086872.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.82 Da
• Isoelectric Point: 5.2314

>NTDB_id=1010368 H1X63_RS01605 WP_084825763.1 293674..294573(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_998]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1010368 H1X63_RS01605 WP_084825763.1 293674..294573(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_998]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	98.662	100	0.987
comR	Streptococcus thermophilus LMD-9	97.993	100	0.98
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425