Detailed information NTG1010004

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H0514_RS08660
• Genome accession: NZ_LR822020
• Coordinates: 1686243..1687142 (-)
• Length: 299 a.a.
• NCBI ID: WP_084825763.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1681243..1692142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS10925	-	1682966..1683313 (+)	348	WP_232086208.1	DUF4153 domain-containing protein	-
H0514_RS08650 (STHERMO_1991)	-	1683534..1683845 (-)	312	WP_095559231.1	DUF805 domain-containing protein	-
H0514_RS10935 (STHERMO_1992)	comA	1683972..1684580 (-)	609	WP_269473452.1	ATP-binding cassette domain-containing protein	Regulator
H0514_RS08655	-	1684596..1686068 (-)	1473	Protein_1671	peptide cleavage/export ABC transporter	-
H0514_RS08660 (STHERMO_1996)	comR	1686243..1687142 (-)	900	WP_084825763.1	helix-turn-helix domain-containing protein	Regulator
H0514_RS08665 (STHERMO_1997)	-	1687313..1688488 (+)	1176	WP_179972202.1	IS256-like element IS1191 family transposase	-
H0514_RS08670 (STHERMO_1999)	-	1688658..1689308 (-)	651	WP_179972602.1	phosphatase PAP2 family protein	-
H0514_RS08675 (STHERMO_2000)	-	1689311..1689868 (-)	558	WP_179972601.1	ECF transporter S component	-
H0514_RS08680 (STHERMO_2001)	-	1690179..1690718 (-)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.82 Da
• Isoelectric Point: 5.2314

>NTDB_id=1010004 H0514_RS08660 WP_084825763.1 1686243..1687142(-) (comR) [Streptococcus thermophilus isolate STH_CIRM_956]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1010004 H0514_RS08660 WP_084825763.1 1686243..1687142(-) (comR) [Streptococcus thermophilus isolate STH_CIRM_956]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	98.662	100	0.987
comR	Streptococcus thermophilus LMD-9	97.993	100	0.98
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.475	100	0.425