Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   H0514_RS01865 Genome accession   NZ_LR822020
Coordinates   353467..354834 (+) Length   455 a.a.
NCBI ID   WP_096811636.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 348467..359834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS01855 (STHERMO_0402) - 348539..350284 (+) 1746 WP_179973259.1 ABC transporter ATP-binding protein -
  H0514_RS01860 (STHERMO_0407) comA/nlmT 351298..353451 (+) 2154 WP_133264081.1 peptide cleavage/export ABC transporter Regulator
  H0514_RS01865 (STHERMO_0408) comB 353467..354834 (+) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator
  H0514_RS01870 (STHERMO_0409) - 354849..355010 (+) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H0514_RS10540 comD/blpH 355028..355831 (-) 804 WP_232086251.1 ATP-binding protein Regulator
  H0514_RS01880 (STHERMO_0411) comE/blpR 356362..357099 (-) 738 WP_179972243.1 LytR/AlgR family response regulator transcription factor Regulator
  H0514_RS01885 (STHERMO_0412) - 357350..357526 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  H0514_RS01890 (STHERMO_0413) - 357545..357745 (+) 201 WP_011681569.1 hypothetical protein -
  H0514_RS01895 (STHERMO_0414) - 358101..358331 (+) 231 WP_011226494.1 bacteriocin class II family protein -
  H0514_RS11110 (STHERMO_0420) - 359354..359755 (+) 402 WP_011226490.1 hypothetical protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50369.08 Da        Isoelectric Point: 4.7492

>NTDB_id=1009939 H0514_RS01865 WP_096811636.1 353467..354834(+) (comB) [Streptococcus thermophilus isolate STH_CIRM_956]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1009939 H0514_RS01865 WP_096811636.1 353467..354834(+) (comB) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACTAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.468

99.121

0.391
  comB Streptococcus pneumoniae D39

39.468

99.121

0.391
  comB Streptococcus pneumoniae R6

39.468

99.121

0.391
  comB Streptococcus pneumoniae TIGR4

38.803

99.121

0.385
  comB Streptococcus mitis SK321

38.137

99.121

0.378
  comB Streptococcus mitis NCTC 12261

38.137

99.121

0.378