Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   H0514_RS01880 Genome accession   NZ_LR822020
Coordinates   356362..357099 (-) Length   245 a.a.
NCBI ID   WP_179972243.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 351362..362099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS01865 (STHERMO_0408) comB 353467..354834 (+) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator
  H0514_RS01870 (STHERMO_0409) - 354849..355010 (+) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H0514_RS10540 comD/blpH 355028..355831 (-) 804 WP_232086251.1 ATP-binding protein Regulator
  H0514_RS01880 (STHERMO_0411) comE/blpR 356362..357099 (-) 738 WP_179972243.1 LytR/AlgR family response regulator transcription factor Regulator
  H0514_RS01885 (STHERMO_0412) - 357350..357526 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  H0514_RS01890 (STHERMO_0413) - 357545..357745 (+) 201 WP_011681569.1 hypothetical protein -
  H0514_RS01895 (STHERMO_0414) - 358101..358331 (+) 231 WP_011226494.1 bacteriocin class II family protein -
  H0514_RS11110 (STHERMO_0420) - 359354..359755 (+) 402 WP_011226490.1 hypothetical protein -
  H0514_RS01900 (STHERMO_0421) - 360006..360260 (+) 255 WP_179972242.1 Blp family class II bacteriocin -
  H0514_RS01905 (STHERMO_0424) cipB 360846..361085 (+) 240 WP_021152514.1 Blp family class II bacteriocin Regulator
  H0514_RS01910 (STHERMO_0425) - 361097..361489 (+) 393 WP_084829084.1 hypothetical protein -
  H0514_RS01915 (STHERMO_0426) - 361518..361697 (+) 180 WP_011681564.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 27979.35 Da        Isoelectric Point: 6.4947

>NTDB_id=1009940 H0514_RS01880 WP_179972243.1 356362..357099(-) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_956]
MKIYLLEDNSIQMGRLEDAVVHELMTFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGRGC

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1009940 H0514_RS01880 WP_179972243.1 356362..357099(-) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_956]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGATGCTGTAGTACATGAACTTATGACCTT
CGGAAAAGATCTATCCTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATTGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATTATCTCTGTCAACTTGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTCCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGAGGATGTTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(146-237)

Response regulator receiver domain (Response_reg)

(26-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.857

100

0.367