Detailed information NTG1009718

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H0511_RS01510
• Genome accession: NZ_LR822017
• Coordinates: 279406..280305 (+)
• Length: 299 a.a.
• NCBI ID: WP_179974221.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_336
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 274406..285305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0511_RS01490 (STHERMO_0289)	-	275859..276368 (+)	510	WP_179974219.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H0511_RS01495 (STHERMO_0290)	-	276679..277236 (+)	558	WP_179972601.1	ECF transporter S component	-
H0511_RS01500 (STHERMO_0291)	-	277239..277889 (+)	651	WP_179974220.1	phosphatase PAP2 family protein	-
H0511_RS01505 (STHERMO_0292)	-	278060..279235 (-)	1176	WP_179972202.1	IS256-like element IS1191 family transposase	-
H0511_RS01510 (STHERMO_0293)	comR	279406..280305 (+)	900	WP_179974221.1	helix-turn-helix domain-containing protein	Regulator
H0511_RS01515 (STHERMO_0294)	comA	280480..281094 (+)	615	WP_179974222.1	cysteine peptidase family C39 domain-containing protein	Regulator
H0511_RS01520 (STHERMO_0295)	comA	281112..281726 (+)	615	WP_179974223.1	ABC transporter transmembrane domain-containing protein	Regulator
H0511_RS01530 (STHERMO_0297)	-	282012..282580 (+)	569	Protein_252	ATP-binding cassette domain-containing protein	-
H0511_RS01535 (STHERMO_0299)	-	282707..283018 (+)	312	WP_095559231.1	DUF805 domain-containing protein	-
H0511_RS09725	-	283239..283586 (-)	348	WP_232086208.1	DUF4153 domain-containing protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35302.78 Da
• Isoelectric Point: 5.2218

>NTDB_id=1009718 H0511_RS01510 WP_179974221.1 279406..280305(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_336]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWQESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1009718 H0511_RS01510 WP_179974221.1 279406..280305(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_336]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGCAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAGGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421