Detailed information NTG1007496

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ABKJ27_RS09180
• Genome accession: NZ_CP157578
• Coordinates: 1893811..1895964 (-)
• Length: 717 a.a.
• NCBI ID: WP_410011748.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_011
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1888811..1900964

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKJ27_RS09165 (ABKJ27_09175)	-	1891427..1891570 (-)	144	WP_078228447.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ABKJ27_RS09170 (ABKJ27_09180)	purC	1891572..1892279 (-)	708	WP_237447385.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ABKJ27_RS09175 (ABKJ27_09185)	comB	1892449..1893798 (-)	1350	WP_410011747.1	competence pheromone export protein ComB	Regulator
ABKJ27_RS09180 (ABKJ27_09190)	comA	1893811..1895964 (-)	2154	WP_410011748.1	peptide cleavage/export ABC transporter ComA	Regulator
ABKJ27_RS09185 (ABKJ27_09195)	-	1896508..1896663 (-)	156	WP_000732248.1	hypothetical protein	-
ABKJ27_RS09190 (ABKJ27_09200)	-	1896688..1896840 (-)	153	WP_001180498.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ABKJ27_RS09195 (ABKJ27_09205)	-	1896964..1897137 (-)	174	WP_000180829.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ABKJ27_RS09200 (ABKJ27_09210)	-	1897171..1897326 (-)	156	WP_049499436.1	hypothetical protein	-
ABKJ27_RS09205 (ABKJ27_09215)	-	1897337..1897465 (-)	129	WP_049499438.1	smi_0059.1 family bacteriocin-like peptide	-
ABKJ27_RS09210 (ABKJ27_09220)	-	1897962..1898693 (-)	732	WP_410011749.1	response regulator transcription factor	-
ABKJ27_RS09215 (ABKJ27_09225)	-	1898690..1899697 (-)	1008	WP_410011750.1	GHKL domain-containing protein	-
ABKJ27_RS09220 (ABKJ27_09230)	-	1900021..1900230 (-)	210	WP_004235961.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80317.32 Da
• Isoelectric Point: 6.5156

>NTDB_id=1007496 ABKJ27_RS09180 WP_410011748.1 1893811..1895964(-) (comA) [Streptococcus sp. KHUD_011]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVTHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNSLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQVLSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMRPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMAFKQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAHGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1007496 ABKJ27_RS09180 WP_410011748.1 1893811..1895964(-) (comA) [Streptococcus sp. KHUD_011]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTGGCTATGGTTTTTGG
CTACTATGGTAGCTATTATTCTTTGGCTCACTTGCGAGAATTGGCCAAGACGACTATGGATGGGACGACGGCTTTGGGAT
TGGTCAAGGTGGCAGAGGAGATTGGCTTTGAGACGCGGGCCATTAAGGCGGATATGACGCTCTTTGACTTGCCAGATTTG
ACTTTTCCTTTTGTTACTCATGTTCTTAAGGAAGGAAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGACCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACGCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATAGTCTGCTCTCTTTTATTCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCTAATATCGTTTTGGCGACACTCTTGGTAACCTTGATTAATATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTGGGGATCATTTCTATTGGGCTGGTTA
TCGTCTATATTCTCCAGCAGGTCTTGTCTTACGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTAATTTTGTCCTATATCAAGCATGTTTTTCACCTACCTATGTCCTTTTTTGCGACACGTCGGACAGGGGAAATCGTGTC
TCGTTTCACGGATGCTAATAGTATCATCGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCGCAAAATACCAATCTCTTTTTCATGACCTTATTGGCACTTCCTATCTATACAGTG
ATTATCTTTGCTTTTATGAGGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGATATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAGATTGACAAGGAAT
TTGTGGACTATCTGAAAAAATCCTTCACCTATAGTCGGGCAGAGAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCATCTC
TTACTCAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTTATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACTAATCCTTTGGAAAATATCATCAACCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTTTATCTGGTAGCTTCTGAGTTTGAGGAGAAGAAAACGGTCGAGGACTTGAGCTTGATG
AAGGGAGATATGGCCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGATGTCTTGTCGGATATCAATTTGACTAT
TCCCCAAGGTTCTAAAGTGGCTTTTGTGGGAATTTCAGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTTT
ATGATCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGGCCTTGCGCCAGTATATC
AACTATCTTCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCAAAGGAGGGAACGAC
TCAAGAGGATATCTTGCGGGCGGTCGAGTTGGCAGAGATTCGGGAGGATATCGAGCGTATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGGATTTCAGGTGGTCAACGTCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATCGCCCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTTGTTGTCTTGGATCAGGGCA
AGATTGTTGAAGAAGGAAAGCATGCTGATTTGCTTGCACATGGTGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	98.466	100	0.985
comA	Streptococcus pneumoniae D39	98.326	100	0.983
comA	Streptococcus pneumoniae R6	98.326	100	0.983
comA	Streptococcus pneumoniae Rx1	98.326	100	0.983
comA	Streptococcus mitis SK321	98.187	100	0.982
comA	Streptococcus pneumoniae TIGR4	97.908	100	0.979
comA	Streptococcus gordonii str. Challis substr. CH1	80.474	100	0.805
comA/nlmT	Streptococcus mutans UA159	65.132	100	0.651