Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ABKJ27_RS05820 Genome accession   NZ_CP157578
Coordinates   1258978..1259652 (-) Length   224 a.a.
NCBI ID   WP_023946427.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1253978..1264652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS05805 (ABKJ27_05820) - 1256264..1257193 (-) 930 WP_049550878.1 peptidase U32 family protein -
  ABKJ27_RS05810 (ABKJ27_05825) - 1257333..1257620 (+) 288 WP_049515680.1 DUF3270 domain-containing protein -
  ABKJ27_RS05815 (ABKJ27_05830) ciaH 1257654..1258988 (-) 1335 WP_078238304.1 two-component system sensor histidine kinase CiaH Regulator
  ABKJ27_RS05820 (ABKJ27_05835) ciaR 1258978..1259652 (-) 675 WP_023946427.1 two-component system response regulator CiaR Regulator
  ABKJ27_RS05825 (ABKJ27_05840) - 1259866..1262412 (-) 2547 WP_410011507.1 M1 family metallopeptidase -
  ABKJ27_RS05830 (ABKJ27_05845) - 1262535..1262975 (-) 441 WP_000188807.1 ASCH domain-containing protein -
  ABKJ27_RS05835 (ABKJ27_05850) - 1263006..1263704 (-) 699 WP_000167120.1 3-oxoacyl-ACP reductase -
  ABKJ27_RS05840 (ABKJ27_05855) - 1263697..1263933 (-) 237 WP_000141914.1 DUF2829 domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25432.27 Da        Isoelectric Point: 4.3283

>NTDB_id=1007466 ABKJ27_RS05820 WP_023946427.1 1258978..1259652(-) (ciaR) [Streptococcus sp. KHUD_011]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKELDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYILKDVQ

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1007466 ABKJ27_RS05820 WP_023946427.1 1258978..1259652(-) (ciaR) [Streptococcus sp. KHUD_011]
ATGATAAAAATCTTATTAGTTGAGGATGACCTAGGCCTGTCAAATTCAGTATTTGACTTTTTAGACGATTTTGCGGATGT
CATGCAGGTTTTTGATGGAGAAGAAGGTCTCTACGAAGCTGAGAGTGGCGTCTATGACTTGATTTTGCTCGATTTGATGT
TGCCAGAAAAAAATGGTTTCCAAGTCTTGAAAGAATTGCGTGAAAAAGGAATTACGACCCCGGTTCTGATCATGACTGCC
AAGGAAAGTTTGGATGACAAGGGACATGGATTTGAACTAGGAGCGGATGATTATCTGACCAAACCTTTCTACCTAGAAGA
ACTCAAAATGCGGATTCAGGCCCTTCTCAAACGTTCAGGTAAGTTTAATGAGAACACCTTAACTTATGGAAATATTGTGG
TTAATCTGTCTACAAATACCGTTAAAGTCGAAGATACTCCTGTCGAATTGCTGGGGAAAGAATTGGATTTACTAGTTTAT
TTCCTTCAAAATCAAAATGTTATTTTGCCGAAGACTCAGATTTTTGATCGTTTATGGGGATTTGATAGTGATACAACGAT
TTCGGTTGTTGAAGTCTATGTTTCAAAAGTCCGTAAGAAATTAAAAGGAACCACTTTTGCAGAGAATTTGCAAACCTTGC
GCAGTGTTGGGTATATTTTAAAAGATGTTCAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

99.107

100

0.991
  ciaR Streptococcus pneumoniae D39

99.107

100

0.991
  ciaR Streptococcus pneumoniae R6

99.107

100

0.991
  ciaR Streptococcus pneumoniae TIGR4

99.107

100

0.991
  ciaR Streptococcus mutans UA159

88.393

100

0.884
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.726

100

0.371
  vicR Streptococcus mutans UA159

35.193

100

0.366

Multiple sequence alignment