Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ABKJ27_RS05815 Genome accession   NZ_CP157578
Coordinates   1257654..1258988 (-) Length   444 a.a.
NCBI ID   WP_078238304.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1252654..1263988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS05800 (ABKJ27_05815) - 1253615..1256065 (-) 2451 WP_410011506.1 bifunctional DnaQ family exonuclease/ATP-dependent helicase -
  ABKJ27_RS05805 (ABKJ27_05820) - 1256264..1257193 (-) 930 WP_049550878.1 peptidase U32 family protein -
  ABKJ27_RS05810 (ABKJ27_05825) - 1257333..1257620 (+) 288 WP_049515680.1 DUF3270 domain-containing protein -
  ABKJ27_RS05815 (ABKJ27_05830) ciaH 1257654..1258988 (-) 1335 WP_078238304.1 two-component system sensor histidine kinase CiaH Regulator
  ABKJ27_RS05820 (ABKJ27_05835) ciaR 1258978..1259652 (-) 675 WP_023946427.1 two-component system response regulator CiaR Regulator
  ABKJ27_RS05825 (ABKJ27_05840) - 1259866..1262412 (-) 2547 WP_410011507.1 M1 family metallopeptidase -
  ABKJ27_RS05830 (ABKJ27_05845) - 1262535..1262975 (-) 441 WP_000188807.1 ASCH domain-containing protein -
  ABKJ27_RS05835 (ABKJ27_05850) - 1263006..1263704 (-) 699 WP_000167120.1 3-oxoacyl-ACP reductase -
  ABKJ27_RS05840 (ABKJ27_05855) - 1263697..1263933 (-) 237 WP_000141914.1 DUF2829 domain-containing protein -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 50682.34 Da        Isoelectric Point: 8.8763

>NTDB_id=1007465 ABKJ27_RS05815 WP_078238304.1 1257654..1258988(-) (ciaH) [Streptococcus sp. KHUD_011]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDTLHGLSNNPQAVIQLAVNRATEEIKDLENAA
TDASKTEIKPNVSSNTEVILFDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEFAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAIKYTEEDGEIDFMISATDRNLYLLVSDNGVGISAEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=1007465 ABKJ27_RS05815 WP_078238304.1 1257654..1258988(-) (ciaH) [Streptococcus sp. KHUD_011]
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTACTTTATCCGCAACTTTGGTGTCTTTACCCTGAT
TTTCTCTACCATGACCTTGATTATTTTGCAGGTCATGCACTCGAGCCTTTATACTTCGGTGGATGATACACTCCATGGCT
TGAGTAACAATCCTCAGGCAGTTATTCAGCTTGCGGTAAATAGGGCAACAGAAGAGATTAAAGATTTAGAGAATGCCGCT
ACAGATGCTAGCAAGACGGAGATAAAACCCAATGTTAGTTCAAATACAGAGGTCATTCTCTTTGATAAGAATTTTACCCA
ACTCCTTTCTGGAAACCGATTTTTGGGCTTGGATAAGATTAAGTTAGAGAAAAAAGAACTAGGCCATATCTATCAGATTC
AGGTTTTTAATAGCTATGGACAGGAAGAAATCTATCGCATGATCTTGATGGAAACGAATATTAGTTCGGTTTCAACCAAT
ATCAAGTATGCGGCTGTCTTGATTAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCATGAGCAATTGATTGTGATTGT
GATGGCAAGTTTCTGGATTTTGTCTTTACTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTAGGCCCCTGCTTGAGAGCA
TGCAGAAACAACAGTCCTTTGTGGAAAATGCTAGTCATGAGTTACGAACTCCACTTGCTGTTTTACAAAATCGTTTAGAG
ACCCTTTTCCGTAAGCCAGAAGCTACCATTATGGATGTGAGTGAAAGCATTGCATCGAGTTTGGAAGAGGTTCGAAATAT
GCGGTTTTTGACGACAAACTTGCTGAACTTAGCTCGTAGAGATGATGGTATTAAGCCGGAATTTGCTGAAGTTCCTACTA
GCTTTTTTAACACGACTTTCACAAACTATGAGATGATTGCTTCTGAAAATGACCGTGTCTTCCGTTTTGAAAATCGCATC
CATCGAACGATTGTCACAGATCAGCTTCTCTTGAAACAATTGATGACCATCCTATTTGATAATGCTATCAAATACACTGA
GGAGGATGGTGAAATTGATTTTATGATTTCAGCGACTGATCGTAATCTTTATTTGCTAGTTTCCGATAATGGAGTCGGTA
TCTCAGCAGAAGATAAGAAGAAAATTTTTGATCGTTTTTATCGAGTGGATAAGGCTAGAACCCGTCAAAAAGGTGGTTTT
GGTTTAGGATTATCCCTAGCCAAGCAAATTGTAGATGCCCTAAAAGGAACCATTACTGTTAAAGATAATAAACCAAAGGG
AACAATTTTTGAAGTGAAGATTGCCATCCACACACCATCTAAAAAGAAAAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(217-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

95.946

100

0.959
  ciaH Streptococcus pneumoniae D39

95.946

100

0.959
  ciaH Streptococcus pneumoniae R6

95.946

100

0.959
  ciaH Streptococcus pneumoniae TIGR4

95.946

100

0.959
  ciaH Streptococcus mutans UA159

55.402

97.973

0.543

Multiple sequence alignment