Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ABKJ27_RS04005 Genome accession   NZ_CP157578
Coordinates   870623..871330 (+) Length   235 a.a.
NCBI ID   WP_020901406.1    Uniprot ID   A0A3B0BL07
Organism   Streptococcus sp. KHUD_011     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 865623..876330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS03980 (ABKJ27_03995) - 865771..866442 (+) 672 WP_000171692.1 GTP pyrophosphokinase family protein -
  ABKJ27_RS03985 (ABKJ27_04000) - 866426..867244 (+) 819 WP_000799056.1 NAD kinase -
  ABKJ27_RS03990 (ABKJ27_04005) - 867241..868137 (+) 897 WP_247927881.1 RluA family pseudouridine synthase -
  ABKJ27_RS03995 (ABKJ27_04010) pta 868181..869155 (+) 975 WP_153199058.1 phosphate acetyltransferase -
  ABKJ27_RS04000 (ABKJ27_04015) mutY 869392..870567 (+) 1176 WP_261031207.1 A/G-specific adenine glycosylase -
  ABKJ27_RS04005 (ABKJ27_04020) micA 870623..871330 (+) 708 WP_020901406.1 response regulator YycF Regulator
  ABKJ27_RS04010 (ABKJ27_04025) micB 871323..872672 (+) 1350 WP_410012092.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ABKJ27_RS04015 (ABKJ27_04030) vicX 872674..873483 (+) 810 WP_410012093.1 MBL fold metallo-hydrolase Regulator
  ABKJ27_RS04020 (ABKJ27_04035) - 873516..873863 (-) 348 WP_410012094.1 thioredoxin -
  ABKJ27_RS04025 (ABKJ27_04040) - 873975..875693 (-) 1719 WP_004254235.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27093.87 Da        Isoelectric Point: 4.6177

>NTDB_id=1007455 ABKJ27_RS04005 WP_020901406.1 870623..871330(+) (micA) [Streptococcus sp. KHUD_011]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQYEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDEKKAQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1007455 ABKJ27_RS04005 WP_020901406.1 870623..871330(+) (micA) [Streptococcus sp. KHUD_011]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAACATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAACGGTCGTGAAGCGCTAGAGCAATATGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATCGATGGTTTAGAAGTTGCTAAGACCATTCGCAAGACTAGTAGTGTGCCTATTATCATGCTTTCGGCT
AAAGATAGCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGGGCGGATGACTATGTAACCAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTCCGTCGCACGGACTTGGTTTCTGTAGATAATCAAGAGTCAGATGAAAAGAAAG
CCCAACCCTTGCAAATTGGGGATTTGGAGATTGTGCCAGATGCTTATGTAGCTAAAAAATATGGTGAAGAACTAGACTTG
ACCCACCGTGAATTTGAGCTCTTGTACCACTTGGCTTCTCATATTGGTCAAGTGATTACACGTGAACACTTGCTTGAAAC
GGTCTGGGGTTATGATTATTTCGGAGATGTTCGAACTGTTGACGTAACTATCAGACGTTTGCGTGAGAAGATTGAAGATA
CACCTAGTCGTCCAGAATATATCCTAACACGTCGTGGTGTTGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3B0BL07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

93.59

99.574

0.932
  vicR Streptococcus mutans UA159

77.872

100

0.779
  covR Streptococcus salivarius strain HSISS4

45.022

98.298

0.443
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.156

98.298

0.434
  scnR Streptococcus mutans UA159

38.034

99.574

0.379

Multiple sequence alignment