Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ABKJ27_RS00215 Genome accession   NZ_CP157578
Coordinates   35743..36405 (+) Length   220 a.a.
NCBI ID   WP_410011783.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 11677..52666 35743..36405 within 0


Gene organization within MGE regions


Location: 11677..52666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS00100 (ABKJ27_00105) - 11677..14220 (-) 2544 WP_049499089.1 YfhO family protein -
  ABKJ27_RS00105 (ABKJ27_00110) - 14280..15902 (-) 1623 WP_000958774.1 ATP-binding cassette domain-containing protein -
  ABKJ27_RS00110 (ABKJ27_00115) trpS 16108..17133 (+) 1026 WP_138704651.1 tryptophan--tRNA ligase -
  ABKJ27_RS00115 (ABKJ27_00120) guaB 17285..18763 (+) 1479 WP_000073418.1 IMP dehydrogenase -
  ABKJ27_RS00120 (ABKJ27_00125) recF 18815..19912 (-) 1098 WP_000266646.1 DNA replication/repair protein RecF -
  ABKJ27_RS00125 (ABKJ27_00130) yaaA 19915..20283 (-) 369 WP_000455896.1 S4 domain-containing protein YaaA -
  ABKJ27_RS00130 (ABKJ27_00135) yfmF 20442..21692 (+) 1251 WP_000424291.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ABKJ27_RS00135 (ABKJ27_00140) yfmH 21689..22972 (+) 1284 WP_410011779.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ABKJ27_RS00140 (ABKJ27_00145) rodZ 23014..23841 (+) 828 WP_285387496.1 cytoskeleton protein RodZ -
  ABKJ27_RS00145 (ABKJ27_00150) pgsA 23852..24397 (+) 546 WP_020900979.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABKJ27_RS00150 (ABKJ27_00155) - 24394..25221 (+) 828 WP_285387495.1 energy-coupling factor ABC transporter ATP-binding protein -
  ABKJ27_RS00155 (ABKJ27_00160) - 25206..26045 (+) 840 WP_000510419.1 energy-coupling factor transporter ATPase -
  ABKJ27_RS00160 (ABKJ27_00165) - 26038..26832 (+) 795 WP_000377896.1 energy-coupling factor transporter transmembrane component T family protein -
  ABKJ27_RS00165 (ABKJ27_00170) mreC 26891..27709 (+) 819 WP_023948193.1 rod shape-determining protein MreC -
  ABKJ27_RS00170 (ABKJ27_00175) mreD 27709..28203 (+) 495 WP_033687609.1 rod shape-determining protein MreD -
  ABKJ27_RS00175 (ABKJ27_00180) pcsB 28297..29544 (+) 1248 WP_000727023.1 peptidoglycan hydrolase PcsB -
  ABKJ27_RS00180 (ABKJ27_00185) rpsB 29770..30549 (+) 780 WP_000268459.1 30S ribosomal protein S2 -
  ABKJ27_RS00185 (ABKJ27_00190) tsf 30628..31668 (+) 1041 WP_000808076.1 translation elongation factor Ts -
  ABKJ27_RS00190 (ABKJ27_00195) tnpA 31855..32319 (+) 465 WP_000057429.1 IS200/IS605 family transposase -
  ABKJ27_RS00195 (ABKJ27_00200) cysK 32545..33471 (-) 927 WP_410011780.1 cysteine synthase A -
  ABKJ27_RS00200 - 33567..33662 (-) 96 Protein_30 PH domain-containing protein -
  ABKJ27_RS00205 (ABKJ27_00205) - 33756..34391 (-) 636 WP_410011781.1 YigZ family protein -
  ABKJ27_RS00210 (ABKJ27_00210) comFA/cflA 34448..35746 (+) 1299 WP_410011782.1 DEAD/DEAH box helicase Machinery gene
  ABKJ27_RS00215 (ABKJ27_00215) comFC/cflB 35743..36405 (+) 663 WP_410011783.1 ComF family protein Machinery gene
  ABKJ27_RS00220 (ABKJ27_00220) hpf 36485..37033 (+) 549 WP_004255322.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ABKJ27_RS00225 (ABKJ27_00225) - 37169..39142 (+) 1974 WP_004255323.1 DHH family phosphoesterase -
  ABKJ27_RS00230 (ABKJ27_00230) rplI 39139..39591 (+) 453 WP_004255324.1 50S ribosomal protein L9 -
  ABKJ27_RS00235 (ABKJ27_00235) dnaB 39635..40987 (+) 1353 WP_004255325.1 replicative DNA helicase -
  ABKJ27_RS00240 (ABKJ27_00240) - 40989..41255 (+) 267 WP_001278169.1 Veg family protein -
  ABKJ27_RS00245 (ABKJ27_00245) cbpD 41450..42568 (+) 1119 WP_410011784.1 choline binding-anchored murein hydrolase CbpD -
  ABKJ27_RS00250 (ABKJ27_00250) - 42823..43113 (+) 291 WP_410011785.1 MTH1187 family thiamine-binding protein -
  ABKJ27_RS00255 (ABKJ27_00255) - 43076..43834 (+) 759 WP_410011786.1 ABC transporter permease -
  ABKJ27_RS00260 (ABKJ27_00260) - 43874..44881 (+) 1008 WP_049501969.1 ABC transporter substrate-binding protein -
  ABKJ27_RS00265 (ABKJ27_00265) - 44881..45609 (+) 729 WP_410011787.1 ABC transporter ATP-binding protein -
  ABKJ27_RS00270 (ABKJ27_00270) - 45728..46186 (+) 459 WP_033687596.1 CtsR family transcriptional regulator -
  ABKJ27_RS00275 (ABKJ27_00275) clpC 46188..48620 (+) 2433 WP_293959280.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ABKJ27_RS00280 (ABKJ27_00280) - 48767..49821 (+) 1055 Protein_46 AAA family ATPase -
  ABKJ27_RS00285 (ABKJ27_00285) pnuC 49831..50610 (+) 780 WP_033687592.1 nicotinamide riboside transporter PnuC -
  ABKJ27_RS00290 (ABKJ27_00290) - 50612..51385 (+) 774 WP_033687591.1 NUDIX domain-containing protein -
  ABKJ27_RS00295 (ABKJ27_00295) - 51459..51689 (-) 231 WP_033687589.1 hypothetical protein -
  ABKJ27_RS00300 (ABKJ27_00300) - 51968..52666 (+) 699 WP_247939257.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25332.15 Da        Isoelectric Point: 5.5140

>NTDB_id=1007427 ABKJ27_RS00215 WP_410011783.1 35743..36405(+) (comFC/cflB) [Streptococcus sp. KHUD_011]
MKCLLCGQTMKAVLTFSSLLLLRNDDSYLCSDCDSTFERIGEENCPNCMKTGLSTKCQDCQFWCKEEVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASVLSEELKKYKEYQFVVIPLSPERLLERGFNQVEGLVEAAEFSLQDLLEKREERASSS
KNRSERLATELPFFVKSGVTIPKKILLIDDIYTTGTTINRVKRLLEEAGAEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1007427 ABKJ27_RS00215 WP_410011783.1 35743..36405(+) (comFC/cflB) [Streptococcus sp. KHUD_011]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGGCTGTTTTAACTTTTAGTAGCCTCTTGCTGTTGAGGAATGATGACTC
CTATCTTTGTTCAGACTGTGATTCTACTTTTGAGAGGATTGGAGAAGAAAACTGCCCAAACTGTATGAAAACAGGTTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGAAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTTTTAAGAAAAGTTTTTGCTTCAGTTTTAAGTGA
GGAGTTAAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGAAAGATTGCTCGAGAGGGGATTTAACC
AGGTTGAAGGTTTAGTTGAAGCAGCAGAGTTCTCTTTGCAAGACTTACTAGAGAAGAGAGAAGAGCGGGCCAGTTCTTCC
AAAAATCGTTCAGAACGCTTGGCAACAGAACTTCCTTTCTTTGTCAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGACATTTATACTACTGGAACAACTATAAATCGTGTGAAGAGATTGCTAGAAGAAGCTGGTGCTGAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(171-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

93.182

100

0.932
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus pneumoniae TIGR4

91.364

100

0.914
  comFC/cflB Streptococcus pneumoniae Rx1

90.909

100

0.909
  comFC/cflB Streptococcus pneumoniae D39

90.909

100

0.909
  comFC/cflB Streptococcus pneumoniae R6

90.909

100

0.909
  comFC Bacillus subtilis subsp. subtilis str. 168

35.526

100

0.368

Multiple sequence alignment