Detailed information
Bioinformatically predicted
Overview
| Name | comFA/cflA | Type | Machinery gene |
| Locus tag | ABKJ27_RS00210 | Genome accession | NZ_CP157578 |
| Coordinates | 34448..35746 (+) | Length | 432 a.a. |
| NCBI ID | WP_410011782.1 | Uniprot ID | - |
| Organism | Streptococcus sp. KHUD_011 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 11677..52666 | 34448..35746 | within | 0 |
Gene organization within MGE regions
Location: 11677..52666
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABKJ27_RS00100 (ABKJ27_00105) | - | 11677..14220 (-) | 2544 | WP_049499089.1 | YfhO family protein | - |
| ABKJ27_RS00105 (ABKJ27_00110) | - | 14280..15902 (-) | 1623 | WP_000958774.1 | ATP-binding cassette domain-containing protein | - |
| ABKJ27_RS00110 (ABKJ27_00115) | trpS | 16108..17133 (+) | 1026 | WP_138704651.1 | tryptophan--tRNA ligase | - |
| ABKJ27_RS00115 (ABKJ27_00120) | guaB | 17285..18763 (+) | 1479 | WP_000073418.1 | IMP dehydrogenase | - |
| ABKJ27_RS00120 (ABKJ27_00125) | recF | 18815..19912 (-) | 1098 | WP_000266646.1 | DNA replication/repair protein RecF | - |
| ABKJ27_RS00125 (ABKJ27_00130) | yaaA | 19915..20283 (-) | 369 | WP_000455896.1 | S4 domain-containing protein YaaA | - |
| ABKJ27_RS00130 (ABKJ27_00135) | yfmF | 20442..21692 (+) | 1251 | WP_000424291.1 | EF-P 5-aminopentanol modification-associated protein YfmF | - |
| ABKJ27_RS00135 (ABKJ27_00140) | yfmH | 21689..22972 (+) | 1284 | WP_410011779.1 | EF-P 5-aminopentanol modification-associated protein YfmH | - |
| ABKJ27_RS00140 (ABKJ27_00145) | rodZ | 23014..23841 (+) | 828 | WP_285387496.1 | cytoskeleton protein RodZ | - |
| ABKJ27_RS00145 (ABKJ27_00150) | pgsA | 23852..24397 (+) | 546 | WP_020900979.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| ABKJ27_RS00150 (ABKJ27_00155) | - | 24394..25221 (+) | 828 | WP_285387495.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
| ABKJ27_RS00155 (ABKJ27_00160) | - | 25206..26045 (+) | 840 | WP_000510419.1 | energy-coupling factor transporter ATPase | - |
| ABKJ27_RS00160 (ABKJ27_00165) | - | 26038..26832 (+) | 795 | WP_000377896.1 | energy-coupling factor transporter transmembrane component T family protein | - |
| ABKJ27_RS00165 (ABKJ27_00170) | mreC | 26891..27709 (+) | 819 | WP_023948193.1 | rod shape-determining protein MreC | - |
| ABKJ27_RS00170 (ABKJ27_00175) | mreD | 27709..28203 (+) | 495 | WP_033687609.1 | rod shape-determining protein MreD | - |
| ABKJ27_RS00175 (ABKJ27_00180) | pcsB | 28297..29544 (+) | 1248 | WP_000727023.1 | peptidoglycan hydrolase PcsB | - |
| ABKJ27_RS00180 (ABKJ27_00185) | rpsB | 29770..30549 (+) | 780 | WP_000268459.1 | 30S ribosomal protein S2 | - |
| ABKJ27_RS00185 (ABKJ27_00190) | tsf | 30628..31668 (+) | 1041 | WP_000808076.1 | translation elongation factor Ts | - |
| ABKJ27_RS00190 (ABKJ27_00195) | tnpA | 31855..32319 (+) | 465 | WP_000057429.1 | IS200/IS605 family transposase | - |
| ABKJ27_RS00195 (ABKJ27_00200) | cysK | 32545..33471 (-) | 927 | WP_410011780.1 | cysteine synthase A | - |
| ABKJ27_RS00200 | - | 33567..33662 (-) | 96 | Protein_30 | PH domain-containing protein | - |
| ABKJ27_RS00205 (ABKJ27_00205) | - | 33756..34391 (-) | 636 | WP_410011781.1 | YigZ family protein | - |
| ABKJ27_RS00210 (ABKJ27_00210) | comFA/cflA | 34448..35746 (+) | 1299 | WP_410011782.1 | DEAD/DEAH box helicase | Machinery gene |
| ABKJ27_RS00215 (ABKJ27_00215) | comFC/cflB | 35743..36405 (+) | 663 | WP_410011783.1 | ComF family protein | Machinery gene |
| ABKJ27_RS00220 (ABKJ27_00220) | hpf | 36485..37033 (+) | 549 | WP_004255322.1 | ribosome hibernation-promoting factor, HPF/YfiA family | - |
| ABKJ27_RS00225 (ABKJ27_00225) | - | 37169..39142 (+) | 1974 | WP_004255323.1 | DHH family phosphoesterase | - |
| ABKJ27_RS00230 (ABKJ27_00230) | rplI | 39139..39591 (+) | 453 | WP_004255324.1 | 50S ribosomal protein L9 | - |
| ABKJ27_RS00235 (ABKJ27_00235) | dnaB | 39635..40987 (+) | 1353 | WP_004255325.1 | replicative DNA helicase | - |
| ABKJ27_RS00240 (ABKJ27_00240) | - | 40989..41255 (+) | 267 | WP_001278169.1 | Veg family protein | - |
| ABKJ27_RS00245 (ABKJ27_00245) | cbpD | 41450..42568 (+) | 1119 | WP_410011784.1 | choline binding-anchored murein hydrolase CbpD | - |
| ABKJ27_RS00250 (ABKJ27_00250) | - | 42823..43113 (+) | 291 | WP_410011785.1 | MTH1187 family thiamine-binding protein | - |
| ABKJ27_RS00255 (ABKJ27_00255) | - | 43076..43834 (+) | 759 | WP_410011786.1 | ABC transporter permease | - |
| ABKJ27_RS00260 (ABKJ27_00260) | - | 43874..44881 (+) | 1008 | WP_049501969.1 | ABC transporter substrate-binding protein | - |
| ABKJ27_RS00265 (ABKJ27_00265) | - | 44881..45609 (+) | 729 | WP_410011787.1 | ABC transporter ATP-binding protein | - |
| ABKJ27_RS00270 (ABKJ27_00270) | - | 45728..46186 (+) | 459 | WP_033687596.1 | CtsR family transcriptional regulator | - |
| ABKJ27_RS00275 (ABKJ27_00275) | clpC | 46188..48620 (+) | 2433 | WP_293959280.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| ABKJ27_RS00280 (ABKJ27_00280) | - | 48767..49821 (+) | 1055 | Protein_46 | AAA family ATPase | - |
| ABKJ27_RS00285 (ABKJ27_00285) | pnuC | 49831..50610 (+) | 780 | WP_033687592.1 | nicotinamide riboside transporter PnuC | - |
| ABKJ27_RS00290 (ABKJ27_00290) | - | 50612..51385 (+) | 774 | WP_033687591.1 | NUDIX domain-containing protein | - |
| ABKJ27_RS00295 (ABKJ27_00295) | - | 51459..51689 (-) | 231 | WP_033687589.1 | hypothetical protein | - |
| ABKJ27_RS00300 (ABKJ27_00300) | - | 51968..52666 (+) | 699 | WP_247939257.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 432 a.a. Molecular weight: 49509.41 Da Isoelectric Point: 8.3101
>NTDB_id=1007426 ABKJ27_RS00210 WP_410011782.1 34448..35746(+) (comFA/cflA) [Streptococcus sp. KHUD_011]
MKVNPNYLGRLFTENELTEEECQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLIMKRVRSDQALYYFPQ
EDFPKQDVLKWSGQLTPFQEKVSEGLIRAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINRGGAVCLASPRIDVCLELYKR
LQKDFVCEIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKKNGLRIFLTATST
DELDRKVRIGELKRLSLPRRFHGNPLIIPKPVWLSDFNHCLEKNRLSPKLKSYIEKQRQTGYPLLIFASEIKKGEQLKEI
LQEQFPNEKIGFVSSVTEDRLEQVQGFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQQMNKEAGL
MKVNPNYLGRLFTENELTEEECQLAEKLPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLIMKRVRSDQALYYFPQ
EDFPKQDVLKWSGQLTPFQEKVSEGLIRAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINRGGAVCLASPRIDVCLELYKR
LQKDFVCEIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKKNGLRIFLTATST
DELDRKVRIGELKRLSLPRRFHGNPLIIPKPVWLSDFNHCLEKNRLSPKLKSYIEKQRQTGYPLLIFASEIKKGEQLKEI
LQEQFPNEKIGFVSSVTEDRLEQVQGFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQQMNKEAGL
Nucleotide
Download Length: 1299 bp
>NTDB_id=1007426 ABKJ27_RS00210 WP_410011782.1 34448..35746(+) (comFA/cflA) [Streptococcus sp. KHUD_011]
ATGAAAGTAAATCCAAATTATCTCGGTCGTTTGTTTACTGAGAATGAATTAACAGAAGAAGAATGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAATTGTTCTGCCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGGGAGTGCTTAATTATGAAGCGAGTTAGAAGTGATCAAGCTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTTAAATGGAGTGGTCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGAT
TCGAGCAGTAGATAAGCAGGAGCCAACCTTGGTACATGCGGTGACAGGGGCTGGAAAGACAGAAATGATTTATCAAGTTG
TGGCTAAGGTGATTAATAGGGGTGGTGCAGTGTGTTTGGCCAGTCCTCGCATAGATGTTTGTTTGGAGCTGTATAAGCGC
CTGCAAAAGGATTTTGTTTGTGAGATAGCCCTCCTACATGGAGAATCAGAACCTTATTTTAGAACACCGCTAGTTGTTGC
GACAACCCATCAGTTATTAAAATTTTATCAAGCTTTTGATTTACTGATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAACCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGAAGAATGGCTTGAGAATCTTTTTAACAGCAACTTCTACC
GATGAGTTAGATAGGAAGGTTCGCATCGGAGAATTAAAACGATTGAGTTTGCCTAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAGCCTGTCTGGTTATCGGATTTTAATCACTGTTTAGAGAAAAATCGGTTGTCACCAAAGTTAAAGTCTTATA
TTGAGAAGCAGAGACAGACAGGTTATCCGTTACTCATTTTTGCATCAGAAATTAAGAAAGGGGAACAGTTAAAAGAAATC
TTACAAGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAACAGGTACAAGGTTT
TCGAGATGGAGAATTGACAATACTTATCAGTACGACGATATTGGAGCGTGGAGTCACCTTCCCTTGTGTTGACGTTTTCG
TCGTAGAGGCCAATCATCGTCTGTTTACCAAGTCTAGCTTGATTCAGATTGGTGGACGAGTTGGTCGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGACGGGCTAAATGCTTCAATCAAGAAGGCAATTAAGGAAATTCAGCAGATGAA
TAAGGAGGCGGGTCTATGA
ATGAAAGTAAATCCAAATTATCTCGGTCGTTTGTTTACTGAGAATGAATTAACAGAAGAAGAATGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAATTGTTCTGCCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGGGAGTGCTTAATTATGAAGCGAGTTAGAAGTGATCAAGCTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTTAAATGGAGTGGTCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGAT
TCGAGCAGTAGATAAGCAGGAGCCAACCTTGGTACATGCGGTGACAGGGGCTGGAAAGACAGAAATGATTTATCAAGTTG
TGGCTAAGGTGATTAATAGGGGTGGTGCAGTGTGTTTGGCCAGTCCTCGCATAGATGTTTGTTTGGAGCTGTATAAGCGC
CTGCAAAAGGATTTTGTTTGTGAGATAGCCCTCCTACATGGAGAATCAGAACCTTATTTTAGAACACCGCTAGTTGTTGC
GACAACCCATCAGTTATTAAAATTTTATCAAGCTTTTGATTTACTGATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAACCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGAAGAATGGCTTGAGAATCTTTTTAACAGCAACTTCTACC
GATGAGTTAGATAGGAAGGTTCGCATCGGAGAATTAAAACGATTGAGTTTGCCTAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAGCCTGTCTGGTTATCGGATTTTAATCACTGTTTAGAGAAAAATCGGTTGTCACCAAAGTTAAAGTCTTATA
TTGAGAAGCAGAGACAGACAGGTTATCCGTTACTCATTTTTGCATCAGAAATTAAGAAAGGGGAACAGTTAAAAGAAATC
TTACAAGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAACAGGTACAAGGTTT
TCGAGATGGAGAATTGACAATACTTATCAGTACGACGATATTGGAGCGTGGAGTCACCTTCCCTTGTGTTGACGTTTTCG
TCGTAGAGGCCAATCATCGTCTGTTTACCAAGTCTAGCTTGATTCAGATTGGTGGACGAGTTGGTCGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGACGGGCTAAATGCTTCAATCAAGAAGGCAATTAAGGAAATTCAGCAGATGAA
TAAGGAGGCGGGTCTATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFA/cflA | Streptococcus mitis NCTC 12261 |
94.907 |
100 |
0.949 |
| comFA/cflA | Streptococcus pneumoniae Rx1 |
93.519 |
100 |
0.935 |
| comFA/cflA | Streptococcus pneumoniae D39 |
93.519 |
100 |
0.935 |
| comFA/cflA | Streptococcus pneumoniae R6 |
93.519 |
100 |
0.935 |
| comFA/cflA | Streptococcus pneumoniae TIGR4 |
93.287 |
100 |
0.933 |
| comFA/cflA | Streptococcus mitis SK321 |
93.056 |
100 |
0.931 |
| comFA | Lactococcus lactis subsp. cremoris KW2 |
49.883 |
99.306 |
0.495 |
| comFA | Latilactobacillus sakei subsp. sakei 23K |
37.931 |
100 |
0.382 |
| comFA | Bacillus subtilis subsp. subtilis str. 168 |
39.012 |
93.75 |
0.366 |