Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ABKJ37_RS16250 Genome accession   NZ_CP157386
Coordinates   3401053..3402372 (+) Length   439 a.a.
NCBI ID   WP_348921034.1    Uniprot ID   -
Organism   Enterococcus rotai strain CMTB-CA6     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3396053..3407372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ37_RS16210 - 3396190..3396380 (-) 191 Protein_3178 transposase -
  ABKJ37_RS16215 - 3396913..3397096 (+) 184 Protein_3179 MerR family transcriptional regulator -
  ABKJ37_RS16220 - 3397062..3397235 (-) 174 WP_348923363.1 hypothetical protein -
  ABKJ37_RS16225 - 3397260..3397682 (-) 423 WP_348921030.1 hypothetical protein -
  ABKJ37_RS16230 - 3398246..3399241 (+) 996 WP_348921031.1 hypothetical protein -
  ABKJ37_RS16235 - 3399367..3399594 (-) 228 WP_348921032.1 hypothetical protein -
  ABKJ37_RS16240 - 3399671..3400117 (-) 447 WP_348921033.1 GNAT family N-acetyltransferase -
  ABKJ37_RS16245 rlmH 3400150..3400629 (-) 480 WP_348923340.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ABKJ37_RS16250 htrA 3401053..3402372 (+) 1320 WP_348921034.1 trypsin-like peptidase domain-containing protein Regulator
  ABKJ37_RS16255 ytpR 3402448..3403065 (-) 618 WP_348921035.1 YtpR family tRNA-binding protein -
  ABKJ37_RS16260 - 3403245..3403706 (-) 462 WP_348921036.1 universal stress protein -
  ABKJ37_RS16265 - 3403768..3404082 (-) 315 WP_348921037.1 thioredoxin family protein -
  ABKJ37_RS16270 pepA 3404093..3405169 (-) 1077 WP_348921038.1 glutamyl aminopeptidase -
  ABKJ37_RS16275 - 3405421..3405762 (+) 342 WP_348921039.1 peptidase -
  ABKJ37_RS16280 - 3405823..3406455 (-) 633 WP_348921040.1 TMEM175 family protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 46064.18 Da        Isoelectric Point: 4.6622

>NTDB_id=1006582 ABKJ37_RS16250 WP_348921034.1 3401053..3402372(+) (htrA) [Enterococcus rotai strain CMTB-CA6]
MQKKDVTPDSDKKQNGLFKKFGIGLVGGLLGGALAFGGAYAIMGQNSPSSNSSTTTSTVKDNKGDTKVTNVSLDVNSDVT
KAVDKVKDSVVSVINLQSPSQNSDANGFGSIFGGNDGSGSDNAESDGSDLQAASEGSGVIYKKDGKTAYVVTNNHVVDQA
KGLEVVLHDGTKVEGELVGTDSYTDLAVIKISSDKVDSIAEFGNSDNLKIGEPALAIGSPLGSAYANSVTQGIISSVNRN
IQNENNGQAININAIQTDAAINPGNSGGPLVNIEGQVIGINSVKIVQSESQVSVEGMGFAIPSNDVVNIINQLEKEGKVT
RPALGITMEELTNVSTQQRKEILKLPESVQMGVLVRSVQTATPADKAGIQRYDVITKIDDKEITSVTDLQSTLYKKKVGD
KMKVTFYRDGKEQSVTVDLTIDQSALKQNSSNSNNSQNP

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1006582 ABKJ37_RS16250 WP_348921034.1 3401053..3402372(+) (htrA) [Enterococcus rotai strain CMTB-CA6]
ATGCAAAAGAAAGACGTTACACCTGATTCAGATAAAAAGCAAAATGGTTTATTCAAAAAATTTGGGATTGGTTTAGTTGG
AGGCTTGCTGGGAGGAGCACTGGCTTTTGGTGGTGCTTATGCTATCATGGGGCAAAATTCCCCTTCATCTAATTCCTCAA
CAACGACTAGCACAGTAAAAGATAATAAGGGCGATACAAAAGTAACCAATGTTAGTTTAGACGTAAATAGCGATGTTACT
AAAGCCGTTGATAAAGTAAAAGATTCAGTCGTTTCAGTCATCAACTTGCAAAGTCCTAGTCAAAATAGTGATGCTAACGG
TTTTGGCAGTATCTTTGGCGGAAATGATGGCAGTGGCTCTGATAATGCTGAGTCTGACGGCAGCGACTTACAAGCCGCCA
GCGAAGGTAGTGGTGTAATCTACAAAAAAGATGGCAAAACTGCTTATGTCGTGACGAATAACCACGTAGTGGATCAAGCA
AAAGGCTTGGAAGTTGTCTTACACGATGGCACTAAAGTAGAAGGCGAATTAGTCGGGACAGATTCTTATACTGACCTTGC
TGTAATCAAAATTTCTTCTGATAAAGTAGACTCAATTGCTGAATTTGGCAATTCTGATAACTTAAAAATCGGAGAACCTG
CTTTAGCGATCGGTTCTCCACTAGGATCAGCTTACGCTAACTCAGTAACACAAGGGATCATTTCATCAGTAAATAGAAAT
ATTCAAAATGAAAATAATGGTCAAGCAATCAATATCAATGCCATTCAAACAGATGCTGCGATCAACCCTGGTAACTCAGG
TGGTCCTTTAGTCAACATTGAAGGTCAAGTAATCGGAATCAACTCTGTTAAAATCGTTCAATCAGAAAGCCAAGTCAGCG
TTGAAGGAATGGGCTTTGCGATTCCAAGTAACGATGTAGTAAATATTATCAATCAATTAGAAAAAGAAGGAAAAGTCACT
CGTCCAGCTTTAGGAATTACAATGGAAGAATTGACAAACGTTTCAACACAACAAAGAAAAGAAATCTTGAAACTTCCAGA
GTCTGTCCAAATGGGCGTACTTGTCCGTTCTGTTCAAACTGCTACTCCAGCAGACAAAGCAGGGATTCAACGATATGATG
TCATTACGAAAATCGATGATAAAGAAATCACTTCTGTAACTGATTTACAAAGTACTCTTTACAAGAAAAAAGTGGGTGAC
AAGATGAAAGTTACTTTCTATCGTGATGGAAAAGAACAAAGTGTTACTGTTGATTTAACAATTGACCAATCAGCACTAAA
ACAAAATTCATCTAACTCAAACAATTCACAAAATCCGTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(136-280)

PDZ domain (PDZ_2)

(322-419)

Peptidase family M50 (Peptidase_M50)

(13-423)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.494

94.533

0.506
  htrA Streptococcus mitis NCTC 12261

51.699

93.85

0.485
  htrA Streptococcus mutans UA159

57.576

82.688

0.476
  htrA Streptococcus pneumoniae TIGR4

57.185

77.677

0.444
  htrA Streptococcus pneumoniae Rx1

57.185

77.677

0.444
  htrA Streptococcus pneumoniae D39

57.185

77.677

0.444
  htrA Streptococcus pneumoniae R6

57.185

77.677

0.444

Multiple sequence alignment