Detailed information NTG1005966

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: FGL22_RS02675
• Genome accession: NZ_LR594048
• Coordinates: 501866..504019 (-)
• Length: 717 a.a.
• NCBI ID: WP_138129336.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 496866..509019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL22_RS02655 (NCTC11556_00548)	comE/blpR	498151..498900 (+)	750	WP_046159788.1	response regulator transcription factor	Regulator
FGL22_RS02660 (NCTC11556_00549)	-	498901..500235 (+)	1335	WP_046159787.1	GHKL domain-containing protein	-
FGL22_RS02665 (NCTC11556_00550)	-	500296..500421 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FGL22_RS02670 (NCTC11556_00551)	-	500512..501855 (-)	1344	WP_138129334.1	bacteriocin secretion accessory protein	-
FGL22_RS02675 (NCTC11556_00552)	comA/nlmT	501866..504019 (-)	2154	WP_138129336.1	peptide cleavage/export ABC transporter	Regulator
FGL22_RS02680 (NCTC11556_00553)	-	504306..504533 (+)	228	WP_002992018.1	Blp family class II bacteriocin	-
FGL22_RS02685 (NCTC11556_00554)	-	504546..504746 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
FGL22_RS02695 (NCTC11556_00556)	-	505041..505235 (+)	195	WP_002990768.1	hypothetical protein	-
FGL22_RS02700 (NCTC11556_00557)	-	505283..505564 (+)	282	WP_046159519.1	hypothetical protein	-
FGL22_RS02705 (NCTC11556_00558)	-	505758..506168 (+)	411	WP_046177598.1	hypothetical protein	-
FGL22_RS10965	-	506415..506662 (+)	248	Protein_474	hypothetical protein	-
FGL22_RS02710	-	506684..506938 (+)	255	WP_184010428.1	CPBP family intramembrane glutamic endopeptidase	-
FGL22_RS02720 (NCTC11556_00560)	-	507324..508040 (+)	717	WP_232089476.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80604.59 Da
• Isoelectric Point: 7.0063

>NTDB_id=1005966 FGL22_RS02675 WP_138129336.1 501866..504019(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGCQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=1005966 FGL22_RS02675 WP_138129336.1 501866..504019(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTTCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGATGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGTA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.727	99.721	0.725
comA	Streptococcus mitis NCTC 12261	67.507	99.582	0.672
comA	Streptococcus mitis SK321	67.087	99.582	0.668
comA	Streptococcus pneumoniae Rx1	67.087	99.582	0.668
comA	Streptococcus pneumoniae D39	67.087	99.582	0.668
comA	Streptococcus pneumoniae R6	67.087	99.582	0.668
comA	Streptococcus pneumoniae TIGR4	66.807	99.582	0.665
comA	Streptococcus gordonii str. Challis substr. CH1	65.877	100	0.66