Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FGL04_RS05120 Genome accession   NZ_LR594035
Coordinates   961264..961938 (+) Length   224 a.a.
NCBI ID   WP_138068433.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 956264..966938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS05110 (NCTC5385_01106) - 956712..959261 (+) 2550 WP_138068432.1 M1 family metallopeptidase -
  FGL04_RS05115 (NCTC5385_01107) - 959461..960941 (+) 1481 Protein_995 IS1182 family transposase -
  FGL04_RS05120 (NCTC5385_01108) ciaR 961264..961938 (+) 675 WP_138068433.1 response regulator transcription factor Regulator
  FGL04_RS05125 (NCTC5385_01109) ciaH 961931..963253 (+) 1323 WP_138068434.1 sensor histidine kinase Regulator
  FGL04_RS05130 (NCTC5385_01110) rpsT 963321..963563 (-) 243 WP_171011245.1 30S ribosomal protein S20 -
  FGL04_RS05135 (NCTC5385_01111) coaA 963623..964543 (-) 921 WP_138068436.1 type I pantothenate kinase -
  FGL04_RS05140 (NCTC5385_01112) - 964808..965398 (+) 591 WP_138068437.1 class I SAM-dependent methyltransferase -
  FGL04_RS05145 (NCTC5385_01113) - 965395..966672 (+) 1278 WP_138068438.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25532.31 Da        Isoelectric Point: 4.3545

>NTDB_id=1005039 FGL04_RS05120 WP_138068433.1 961264..961938(+) (ciaR) [Streptococcus pseudoporcinus strain NCTC5385]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFNENSITFGNLRVDLDRNAVKVNGSAVELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTDFATNLQTLRSVGYILKADD

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1005039 FGL04_RS05120 WP_138068433.1 961264..961938(+) (ciaR) [Streptococcus pseudoporcinus strain NCTC5385]
ATGATAAAAATATTACTAGTTGAAGATGATTTAAGTTTATCGAATTCTATTTTTGACTTTCTCGATGATTTTGCTGATGT
TATGCAAGTTTTTGATGGAGATGAAGGTTTATATGAAGCAGAAAGTGGGGTTTATGATTTAATTCTTTTAGATTTAATGC
TCCCAGAAAAAAATGGCTTTCAAGTTCTAAAAGAGCTTAGAGAAAAGGATATTAAGACCCCTGTTTTAATTATGACTGCT
AAAGAAGGGTTAGATGATAAGGGACATGGTTTTGAATTAGGTGCTGATGACTATTTAACCAAGCCTTTTTACTTGGAAGA
ACTTAAAATGCGTATTCAAGCCCTTCTTAAACGAACTGGTAAGTTTAACGAAAACAGTATTACGTTTGGTAATCTCAGAG
TTGACCTTGATCGGAATGCTGTGAAAGTGAATGGTAGTGCTGTTGAACTATTAGGGAAAGAATATGATCTGCTCATCTAT
TTACTTCAAAATCAGAATGTTATTTTACCGAAATCCCAAATTTTTGATCGGATTTGGGGTTTTGATAGTGATACCACTAT
CTCGGTCGTGGAAGTTTATGTTTCTAAAATTCGAAAGAAATTAAAAGATACTGATTTTGCAACAAACTTACAGACCTTAC
GTAGCGTTGGCTACATTTTAAAAGCCGATGACTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.14

98.661

0.879
  ciaR Streptococcus pneumoniae Rx1

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae D39

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae TIGR4

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae R6

86.425

98.661

0.853
  vicR Streptococcus mutans UA159

36.864

100

0.388
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379

Multiple sequence alignment