Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL04_RS05125 Genome accession   NZ_LR594035
Coordinates   961931..963253 (+) Length   440 a.a.
NCBI ID   WP_138068434.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 956931..968253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS05115 (NCTC5385_01107) - 959461..960941 (+) 1481 Protein_995 IS1182 family transposase -
  FGL04_RS05120 (NCTC5385_01108) ciaR 961264..961938 (+) 675 WP_138068433.1 response regulator transcription factor Regulator
  FGL04_RS05125 (NCTC5385_01109) ciaH 961931..963253 (+) 1323 WP_138068434.1 sensor histidine kinase Regulator
  FGL04_RS05130 (NCTC5385_01110) rpsT 963321..963563 (-) 243 WP_171011245.1 30S ribosomal protein S20 -
  FGL04_RS05135 (NCTC5385_01111) coaA 963623..964543 (-) 921 WP_138068436.1 type I pantothenate kinase -
  FGL04_RS05140 (NCTC5385_01112) - 964808..965398 (+) 591 WP_138068437.1 class I SAM-dependent methyltransferase -
  FGL04_RS05145 (NCTC5385_01113) - 965395..966672 (+) 1278 WP_138068438.1 pyrimidine-nucleoside phosphorylase -
  FGL04_RS05150 (NCTC5385_01114) deoC 966682..967344 (+) 663 WP_138068439.1 deoxyribose-phosphate aldolase -
  FGL04_RS05155 (NCTC5385_01115) - 967331..967720 (+) 390 WP_138068440.1 cytidine deaminase -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 50253.67 Da        Isoelectric Point: 8.7977

>NTDB_id=1005040 FGL04_RS05125 WP_138068434.1 961931..963253(+) (ciaH) [Streptococcus pseudoporcinus strain NCTC5385]
MTKYRAIITSDNFDRFFHFFAVFTGIFVVMTVIILQIMKVGVYSSVDTSLTAVATHSTLYANRTMERISSFYFDGQDFNF
KTNLDDLKGKNSDQPVANTDIILFNANGMVINTFDALSNFQNFSFKKSDLNEIKTIKLVNYYGHEEKFHTITVRVHSNNY
PAVAYLMAVVNVEQSEKTNERYEKIIIIIMILFWLISILASIYLANWSNKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNESILDNSEAIASSLEEVRNMRILTTNLLNLARRDDGIKPEIVEISSHFFDGIFDNYKLIAEDYGKGFESVN
GVTKPIRMDKSLLKQLMTILFDNAIKYTDESGFIKITVRNTDKYFFITVEDNGPGIRDADKKKIFDRFYRVDKARTRSHG
GFGLGLSLAQQIVTSLKGTILVNDNKGKGSVFEVKLPLSG

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1005040 FGL04_RS05125 WP_138068434.1 961931..963253(+) (ciaH) [Streptococcus pseudoporcinus strain NCTC5385]
ATGACTAAATATAGAGCTATTATTACATCAGATAATTTTGACCGTTTCTTTCATTTCTTTGCCGTTTTTACAGGTATATT
TGTTGTTATGACGGTTATTATTTTGCAAATTATGAAAGTGGGCGTTTACTCATCAGTAGATACAAGCTTGACAGCTGTTG
CGACTCATTCAACCCTCTATGCTAATCGAACTATGGAAAGGATTTCCTCTTTCTATTTTGATGGTCAAGACTTCAATTTT
AAAACAAACCTAGATGATTTAAAAGGGAAAAATAGTGATCAACCCGTCGCAAATACTGATATTATTTTATTTAATGCTAA
TGGTATGGTGATTAATACCTTTGATGCGCTTTCTAATTTTCAAAATTTCTCTTTTAAAAAGAGTGATTTAAACGAAATCA
AAACCATAAAATTGGTTAATTATTACGGTCATGAGGAAAAATTTCATACTATTACGGTTAGAGTTCATTCTAACAACTAC
CCAGCTGTTGCTTATTTAATGGCTGTTGTGAACGTAGAGCAATCTGAAAAAACGAATGAACGCTATGAAAAAATAATTAT
TATCATTATGATTCTATTTTGGCTTATTTCTATTTTGGCAAGTATCTATTTAGCCAATTGGAGTAACAAACCAATTCTCG
AAAGCTATGAAAAACAGAAGATGTTTGTTGAAAATGCCAGTCATGAATTAAGAACGCCTTTGGCTGTGCTCCAAAATCGT
TTAGAGACCCTTTTTCGCAAGCCCAACGAGAGTATTTTGGATAATAGCGAAGCAATTGCCTCAAGCTTGGAAGAGGTTCG
AAACATGAGAATATTAACAACTAATCTTCTGAACTTAGCTCGTCGGGATGATGGTATTAAACCTGAAATTGTAGAAATAT
CGAGTCACTTTTTTGATGGTATTTTTGACAATTATAAACTCATTGCTGAAGATTATGGAAAAGGTTTTGAGTCTGTTAAT
GGCGTTACTAAGCCAATCAGAATGGATAAGTCCCTTCTAAAACAATTAATGACAATTTTATTCGATAATGCAATTAAATA
TACAGATGAATCAGGTTTTATTAAAATAACTGTTAGAAACACAGATAAATATTTCTTTATTACTGTTGAAGATAATGGAC
CGGGGATTAGAGATGCTGACAAAAAGAAAATATTTGACCGTTTTTATCGAGTAGATAAAGCAAGAACAAGAAGTCATGGT
GGCTTTGGATTAGGTTTGTCACTGGCTCAACAAATCGTCACTTCCTTAAAGGGGACTATTCTTGTTAATGATAATAAAGG
CAAGGGGAGTGTCTTTGAGGTTAAACTTCCTCTAAGTGGTTAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.293

99.318

0.559
  ciaH Streptococcus pneumoniae Rx1

47.865

100

0.484
  ciaH Streptococcus pneumoniae D39

47.865

100

0.484
  ciaH Streptococcus pneumoniae R6

47.865

100

0.484
  ciaH Streptococcus pneumoniae TIGR4

47.865

100

0.484