Detailed information NTG1001811

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ABC807_RS01145
• Genome accession: NZ_CP156625
• Coordinates: 219804..220265 (+)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TL7/1993
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 214804..225265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC807_RS01110 (ABC807_01110)	-	215299..216357 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
ABC807_RS01115 (ABC807_01115)	-	216508..216873 (+)	366	WP_000286415.1	DUF1033 family protein	-
ABC807_RS01120 (ABC807_01120)	comGA/cglA/cilD	216949..217890 (+)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
ABC807_RS01125 (ABC807_01125)	comGB/cglB	217838..218854 (+)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABC807_RS01130 (ABC807_01130)	comGC/cglC	218856..219179 (+)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
ABC807_RS01135 (ABC807_01135)	comGD/cglD	219142..219576 (+)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
ABC807_RS01140 (ABC807_01140)	comGE/cglE	219539..219841 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ABC807_RS01145 (ABC807_01145)	comGF/cglF	219804..220265 (+)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABC807_RS01150 (ABC807_01150)	comGG/cglG	220243..220635 (+)	393	WP_050202681.1	competence type IV pilus minor pilin ComGG	Machinery gene
ABC807_RS01155 (ABC807_01155)	-	220791..221383 (+)	593	Protein_211	methyltransferase domain-containing protein	-
ABC807_RS01160 (ABC807_01160)	comYH	221444..222397 (+)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
ABC807_RS01165 (ABC807_01165)	-	222448..223638 (+)	1191	WP_000167765.1	acetate kinase	-
ABC807_RS01170 (ABC807_01170)	-	223639..223770 (+)	132	WP_000768904.1	hypothetical protein	-
ABC807_RS01175 (ABC807_01175)	rnpA	223787..224158 (+)	372	WP_000739246.1	ribonuclease P protein component	-
ABC807_RS01180 (ABC807_01180)	-	224133..224957 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=1001811 ABC807_RS01145 WP_000250531.1 219804..220265(+) (comGF/cglF) [Streptococcus pneumoniae strain TL7/1993]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=1001811 ABC807_RS01145 WP_000250531.1 219804..220265(+) (comGF/cglF) [Streptococcus pneumoniae strain TL7/1993]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915