Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE/cglE   Type   Machinery gene
Locus tag   ABC807_RS01140 Genome accession   NZ_CP156625
Coordinates   219539..219841 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TL7/1993     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 214539..224841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC807_RS01110 (ABC807_01110) - 215299..216357 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  ABC807_RS01115 (ABC807_01115) - 216508..216873 (+) 366 WP_000286415.1 DUF1033 family protein -
  ABC807_RS01120 (ABC807_01120) comGA/cglA/cilD 216949..217890 (+) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  ABC807_RS01125 (ABC807_01125) comGB/cglB 217838..218854 (+) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABC807_RS01130 (ABC807_01130) comGC/cglC 218856..219179 (+) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  ABC807_RS01135 (ABC807_01135) comGD/cglD 219142..219576 (+) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABC807_RS01140 (ABC807_01140) comGE/cglE 219539..219841 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABC807_RS01145 (ABC807_01145) comGF/cglF 219804..220265 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABC807_RS01150 (ABC807_01150) comGG/cglG 220243..220635 (+) 393 WP_050202681.1 competence type IV pilus minor pilin ComGG Machinery gene
  ABC807_RS01155 (ABC807_01155) - 220791..221383 (+) 593 Protein_211 methyltransferase domain-containing protein -
  ABC807_RS01160 (ABC807_01160) comYH 221444..222397 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  ABC807_RS01165 (ABC807_01165) - 222448..223638 (+) 1191 WP_000167765.1 acetate kinase -
  ABC807_RS01170 (ABC807_01170) - 223639..223770 (+) 132 WP_000768904.1 hypothetical protein -
  ABC807_RS01175 (ABC807_01175) rnpA 223787..224158 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=1001810 ABC807_RS01140 WP_000413382.1 219539..219841(+) (comGE/cglE) [Streptococcus pneumoniae strain TL7/1993]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1001810 ABC807_RS01140 WP_000413382.1 219539..219841(+) (comGE/cglE) [Streptococcus pneumoniae strain TL7/1993]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1

  comGE/cglE Streptococcus pneumoniae D39

100

100

1

  comGE/cglE Streptococcus pneumoniae R6

100

100

1

  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1

  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98

  comGE/cglE Streptococcus mitis SK321

98

100

0.98

  comYE Streptococcus mutans UA140

44.444

90

0.4

  comYE Streptococcus mutans UA159

44.444

90

0.4


Multiple sequence alignment