Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL130_RS03295 Genome accession   NZ_LR134320
Coordinates   629235..630131 (+) Length   298 a.a.
NCBI ID   WP_002283255.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 624235..635131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS03265 (NCTC10832_00616) - 625150..625713 (+) 564 WP_002262916.1 nucleotidyltransferase family protein -
  EL130_RS03270 (NCTC10832_00617) - 626140..627153 (+) 1014 WP_002262915.1 YdcF family protein -
  EL130_RS03275 (NCTC10832_00618) - 627230..628006 (+) 777 WP_002266499.1 MBL fold metallo-hydrolase -
  EL130_RS03280 (NCTC10832_00619) tadA 628006..628476 (+) 471 WP_002283908.1 tRNA adenosine(34) deaminase TadA -
  EL130_RS03285 (NCTC10832_00620) - 628473..629036 (+) 564 WP_002262912.1 hypothetical protein -
  EL130_RS03295 (NCTC10832_00622) comR 629235..630131 (+) 897 WP_002283255.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 298 a.a.        Molecular weight: 34700.85 Da        Isoelectric Point: 4.5183

>NTDB_id=1001561 EL130_RS03295 WP_002283255.1 629235..630131(+) (comR) [Streptococcus mutans strain NCTC10832]
MSIKETIGKKIREVREEKGLSREQLCDTEEELTVRQLVRIELGQSLPSIVKLEYIAKVLETDLGTLLAGESITIPEEYFT
MKYQLFKFPSYGDSERLAQKTQMIEDIYEKYFDVLTEEELFTLELLDNSLDYISTRKTAAAEDIFEDFFKQLLTKKHYSF
NDLLLAKYYAIQCQDKDYKEITLQILETTILQQDVSGDEYYNIELLGVLTAIAGVYLDHGLYYKLKALVVKMDDIISKTQ
QYSIKPGLLMFEAKYYLYAEYDKKKAKECYDLAALLAQNFGDKVLEANIFSERKKDQL

Nucleotide


Download         Length: 897 bp        

>NTDB_id=1001561 EL130_RS03295 WP_002283255.1 629235..630131(+) (comR) [Streptococcus mutans strain NCTC10832]
ATGAGCATAAAAGAAACAATTGGGAAAAAGATTAGGGAAGTTCGTGAGGAAAAGGGTTTATCACGTGAACAATTGTGTGA
CACTGAAGAAGAACTAACAGTTCGCCAGTTGGTACGTATCGAGCTAGGACAGTCTTTACCCTCTATTGTAAAATTGGAAT
ACATTGCAAAAGTATTAGAAACTGATTTAGGAACTTTACTTGCAGGTGAAAGTATTACTATACCAGAAGAGTATTTCACT
ATGAAGTATCAACTTTTCAAATTTCCCAGTTATGGTGATTCTGAACGCTTAGCTCAAAAAACGCAAATGATTGAAGATAT
TTATGAAAAGTATTTTGATGTTTTGACGGAGGAGGAACTTTTTACTTTAGAATTACTAGATAACTCTCTAGATTATATTT
CAACAAGAAAAACGGCAGCAGCAGAAGATATCTTTGAAGATTTTTTTAAACAACTTTTAACAAAAAAACATTATTCTTTC
AATGATTTATTATTGGCAAAGTACTATGCTATTCAATGTCAGGATAAAGATTATAAGGAAATAACCTTGCAGATACTCGA
AACGACTATTTTACAGCAAGATGTCTCAGGTGATGAGTATTACAATATTGAACTTTTAGGAGTGTTGACAGCTATAGCAG
GAGTTTATTTAGATCATGGTTTATATTATAAATTAAAGGCTTTGGTCGTTAAAATGGATGATATCATCTCTAAAACGCAA
CAATATAGTATTAAACCTGGATTATTAATGTTTGAAGCAAAATATTATCTCTATGCTGAATATGATAAAAAGAAAGCAAA
GGAATGTTATGATTTAGCTGCTTTACTAGCACAGAATTTTGGAGATAAAGTTTTAGAAGCTAATATCTTTTCTGAAAGAA
AAAAGGATCAGCTTTAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)

Helix-turn-helix (HTH_3)

(11-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius SK126

42.475

100

0.426
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.424

99.664

0.423
  comR Streptococcus thermophilus LMG 18311

41.806

100

0.419
  comR Streptococcus salivarius strain HSISS4

41.806

100

0.419
  comR Streptococcus thermophilus LMD-9

41.472

100

0.416
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

40.404

99.664

0.403

Multiple sequence alignment