Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   EL139_RS02670 Genome accession   NZ_LR134316
Coordinates   492786..493817 (-) Length   343 a.a.
NCBI ID   WP_111717873.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 487786..498817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS02630 (NCTC6181_00536) - 488246..488452 (-) 207 WP_111714788.1 helix-turn-helix transcriptional regulator -
  EL139_RS02635 (NCTC6181_00537) - 488758..489954 (-) 1197 WP_111714785.1 acetate kinase -
  EL139_RS02640 (NCTC6181_00538) comGH 490013..490966 (-) 954 WP_111714783.1 class I SAM-dependent methyltransferase Machinery gene
  EL139_RS02645 (NCTC6181_00539) comGG 491029..491403 (-) 375 WP_111714780.1 competence type IV pilus minor pilin ComGG -
  EL139_RS02650 (NCTC6181_00540) comGF 491381..491821 (-) 441 WP_111714778.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL139_RS02655 (NCTC6181_00541) comGE 491802..492047 (-) 246 WP_231871990.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL139_RS02660 (NCTC6181_00542) comGD 492055..492483 (-) 429 WP_111714773.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL139_RS02665 (NCTC6181_00543) comGC 492458..492784 (-) 327 WP_111714771.1 competence type IV pilus major pilin ComGC Machinery gene
  EL139_RS02670 (NCTC6181_00544) comGB 492786..493817 (-) 1032 WP_111717873.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL139_RS02675 (NCTC6181_00545) comGA/cglA 493753..494694 (-) 942 WP_111714768.1 competence type IV pilus ATPase ComGA Machinery gene
  EL139_RS02680 (NCTC6181_00546) - 494775..495140 (-) 366 WP_003055257.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38955.31 Da        Isoelectric Point: 8.9053

>NTDB_id=1001333 EL139_RS02670 WP_111717873.1 492786..493817(-) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MTFLQQDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLTEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLETQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1001333 EL139_RS02670 WP_111717873.1 492786..493817(-) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATCACCTTCTTGCAGCAGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGACTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAACTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGTTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAACTTTTTACTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA140

53.982

98.834

0.534
  comGB Streptococcus mutans UA159

53.982

98.834

0.534
  comGB Streptococcus gordonii str. Challis substr. CH1

48.673

98.834

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

45.97

97.668

0.449
  comGB/cglB Streptococcus mitis SK321

45.345

97.085

0.44
  comGB/cglB Streptococcus pneumoniae Rx1

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae D39

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae R6

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae TIGR4

43.844

97.085

0.426
  comGB Lactococcus lactis subsp. cremoris KW2

42.773

98.834

0.423

Multiple sequence alignment